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Merck · 1 day ago

Associate Principal Pharmaceutical Commercialization Scientist (Engineer)

West Point, PA

Full-time

Hybrid

Senior Level, Lead/Staff

$142K/yr - $224K/yr

4+ years exp

Merck is a leading pharmaceutical company seeking an Associate Principal Scientist (Engineer) for their Pharmaceutical Commercialization Technology (PCT) team. This role involves overseeing process development activities for late-stage pharmaceutical projects, leading teams, and ensuring effective collaboration with partner groups to drive technical excellence and support regulatory filings.

BiotechnologyHealth CareMedicalPharmaceutical

Comp. & Benefits

No H1B

Responsibilities

Decides on development plans and outcomes for Final Market Formulations and commercial processes

As project team leader, develops high-performing teams, or as a key member of multiple smaller teams influences direction for optimal solutions based on use of systematic planning, risk and options analysis tools. Escalates issues appropriately for visibility and resolution

Acts as Subject Matter Expert (SME) in technical areas in order to efficiently solve problems using appropriate tools and prior knowledge

Has fluency of scientific/technical concepts and techniques, applies and furthers those concepts and techniques in pursuit of resolving scientific/technical issues

Supports technical capability build and knowledge sharing within organization

Technical depth and breadth in all aspects of solid dosage form and process development, including standard and enabled formulations and processes, characterization techniques, experimental data analysis and modeling, including statistical and first principal approaches

Leads application of process development in accordance with ICH principles in regulatory filings, with an emphasis on process robustness and flexibility with business benefits using enhanced and traditional control strategies

Makes informed cost/benefit decisions based on analysis of inputs, risk and likely return, and takes ownership of the outcomes

Influences departmental strategy and tactics, particularly with regard to technical issues

Leverages communication mechanisms and business processes to facilitate decision making and leverages the collective experience of the organization

Influences interactions with key partner groups, and helps to set strategy and tactics across functions

Qualification

Process DevelopmentOral Solid Dosage FormsStatistical LiteracyDesign of Experiments (DOE)Data AnalyticsProcess OptimizationProcess Scale UpProcess DesignTechnical WritingDetail-Oriented

Required

Minimum education and experience: B.S., M.S., or PhD in Engineering, Chemistry, or related engineering/scientific discipline required

Relevant experience (B.S. +7 years, M.S. + 5 years, or PhD + 4 years) in oral solid dosage drug product development or closely related area

Data Analytics

Design of Experiments (DOE)

Detail-Oriented

Process Design

Process Optimization

Process Scale Up

Solid Dosage Forms

Statistical Literacy

Preferred

Spray Drying for Amorphous Solid Dispersions

Bilayer Compression

Process or formulation development for Peptide drug products and/or formulations using permeation enhancement

Process modelling, Discrete Element Modelling (DEM), Computational Fluid Dynamics (CFD)

Data analysis and digital expertise, including digital fluency in one or more of these areas: python, R, powerBI, power apps, Generative AI as a productivity tool, data literacy and statistical reasoning

Technology Transfer between Sites