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CHEManager International · 3 days ago

Lab Core - Metabolics Laboratory Sr Scientist

Dallas, TX

Full-time

Onsite

Mid, Senior Level

3+ years exp

Children's Health is dedicated to improving children's health through innovative treatments and partnerships. The Metabolics Laboratory Senior Scientist will lead clinical assay development and validation in a CAP/CLIA certified lab while providing guidance to clinical staff and promoting continuous process improvement.

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Responsibilities

Direct activities of Sr Laboratory Scientist toward achieving project objectives and provide technical leadership and guidance to the clinical staff

Perform clinical assay design, development, optimization, validation, verification, and result evaluation with autonomy. Work with laboratory manager, supervisor and clinical staff to improve protocols, evaluate new techniques, and develop strategies for their implementation

Report findings and updates to the Manager, supervisor and Clinical Consultant, and as needed to other physicians. Prepare and maintain SOPs for processes and instruments

Assist with preparation of the laboratory to comply with regulatory guidelines. Understand and adhere to Lean principles and processes such as standard work and maintaining 5S concept in work area realizing that all processes are driven by the needs of the customer

Using an awareness of how the work performed is valued by the customer, perform duties, make decisions, take actions and continually strive to improve work processes

Establish and maintain close working relationships with colleagues, manager, and clinical consultant

Maintain current knowledge of related literature in clinical assays. Assist in writing publications results

Align daily work with individual, section, departmental and organizational goals and objectives. Actively looks for ways to improve standard work processes and shares insights to that end with team members with the same level of importance as performing quality technical work

Promote a trusting and secure work environment through supportive, dependable interactions

Take ownership of performance and PEAC process by understanding lab goals and objectives and align individual activities with hospital and lab goals and objectives

Operate, troubleshoot, and maintain GC-MS, LC-MS/MS, LC-QTOF instruments and related laboratory equipment to ensure optimal performance

Develop, validate and refine clinical assays for the analysis of drugs, metabolites, hormones, and other substances in biological matrices

Analyze and interpret chromatography and mass spectrometry data, ensuing accuracy and reliability

Collaborate with pathologists, laboratory and clinical staff to enhance patient care through accurate and timely testing results

Enhance compliance with hospital policies, laboratory safety protocols, and regulatory standards (e.g., CLIA, CAP)

Provide technical expertise and training to laboratory staff on chromatography and mass spectrometry techniques and safety procedures

Participate in quality assurance and quality control activities to maintain laboratory accreditation

Contribute to research and development initiatives within the chemistry/Metabolics lab to advance laboratory capabilities. Document and report findings accurately, maintaining detailed laboratory records, and reagent inventory

Participate in tracers, mock inspections, regulatory review, and help with other duties as required. Attend and participate in stand-up meetings, staff meetings and Laboratory Town Hall meetings

Share knowledge and provide instructions to new employees, students, specialists, and other staff and participate in training of said individuals

Qualification

Mass spectrometryChromatographic techniquesTechnical assay developmentData processing softwareClinical laboratory experienceLean principlesTrainingProblem-solving skillsTeam collaborationMentoring

Required

Proficiency in operating mass spectrometry

Proficiency in understanding chromatographic techniques

At least 3 years in mass spectrometry, preferably in a clinical or toxicology laboratory setting

Preferred

Technical Assay development and validation experience

Ability to provide introduction of new or improved clinical assays to clinical staff

Competence with data processing with Sciex OS, Waters, Agilent technologies software

Must be certified or certification eligible in medical technology with acquisition of certification within 12 months of hire, or have special competence in a specific discipline germane to the position, as determined by the Chief of Pathology

Individuals possessing a bachelor's degree in a scientific discipline other than medical technology (such as biology or chemistry) and who are performing in a specialized area of medical technology (such as molecular testing) and who are seeking categorical certification in this targeted area will have 12 months to complete their certification. Extensions beyond 12 months can be approved by the Chief of Pathology provided competence in patient testing activities is documented in compliance with CLIA