Senior Cell Biologist, Tissue Engineer jobs in United States
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Draper · 1 week ago

Senior Cell Biologist, Tissue Engineer

Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The Bioengineering Division is seeking a Senior Cell Biologist, Tissue Engineer, to support the research and development of cutting-edge technologies, focusing on innovative bioengineering solutions and mentoring less experienced bioengineers.

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Responsibilities

Drive solutions to complex problems with limited direction
Contribute to the development of innovative bioengineering solutions, propose ways forward, and adapt appropriately to changes in requirements
Able to provide insight and suggest design modifications based on analysis outcomes
Actively mentor less experienced bioengineers and provide thoughtful, constructive feedback
Performs other duties as assigned
Apply cell biology, developmental biology, and tissue engineering fundamentals to establish novel cell and tissue models and assays within Draper’s in vitro tissue culture systems under different contexts of use
Plan, conduct, and lead technical experiments with Draper’s advanced in vitro tissue culture technologies (microphysiological system or organs-on-chip) in Draper's biosafety level 2 (BSL-2) laboratory
Culture, maintain, and manipulate human primary cells and tissues in standard in vitro culture systems and within Draper’s advanced MPS platform technologies
Perform a variety of standard molecular, biochemical, cellular, and analytical assays (e.g. immunostaining, ELISA, Luminex, qPCR)
Conduct brightfield, fluorescent and high-content confocal microscopy, collect and analyze image datasets, and extract meaningful biological insights from images using image analysis
Help create, document, maintain and execute experimental protocols (SOPs) and analytical methods to be compatible with Draper’s platform technologies
Collect, interpret, summarize, and effectively present data to project team leads, internal management, and external sponsors/customers via presentations and for publication
Work collaboratively with team(s) to execute project plans, and mentor and support colleagues at the bench through teamwork
Troubleshoot experimental work in coordination with colleagues and project leadership
Complete all necessary training, adhere to all laboratory, institutional, and government regulations, and contribute to an environment of safety and compliance
Support business development efforts through technical ideation, proposal writing, and customer outreach as needed
Support lab organization and maintenance as needed, such as sourcing and preparation of reagents and materials

Qualification

Cell BiologyTissue EngineeringMicrophysiological SystemsMammalian Cell CultureImmunologyBiochemical AssaysConfocal MicroscopyExperimental ProtocolsMicrosoft OfficeTeam CollaborationProblem SolvingCommunication SkillsTime Management

Required

A minimum of a Bachelor's Degree in Bioengineering, Biomedical Engineering, Biochemistry, Chemistry, Cell Biology, Immunology, Microbiology, Molecular Biology, Mechanical Engineering, Chemical Engineering, Physics or related fields is required
Requires 5-7 years of Bioengineering or related engineering experience
Strong foundation in biology and/or engineering principles
Team player, dedicated, collaborative, observant, and motivated
Excellent organizational skills, attention to detail, and verbal and written communication skills
Creative problem-solving skills and a passion for innovation
Excellent time management skills with the proven ability to meet deadlines and prioritize tasks
Enthusiasm for learning and participating in mentorship/mentoring
Proficiency with Microsoft Office Applications
Apply cell biology, developmental biology, and tissue engineering fundamentals to establish novel cell and tissue models and assays within Draper's in vitro tissue culture systems under different contexts of use
Plan, conduct, and lead technical experiments with Draper's advanced in vitro tissue culture technologies (microphysiological system or organs-on-chip) in Draper's biosafety level 2 (BSL-2) laboratory
Culture, maintain, and manipulate human primary cells and tissues in standard in vitro culture systems and within Draper's advanced MPS platform technologies
Perform a variety of standard molecular, biochemical, cellular, and analytical assays (e.g. immunostaining, ELISA, Luminex, qPCR)
Conduct brightfield, fluorescent and high-content confocal microscopy, collect and analyze image datasets, and extract meaningful biological insights from images using image analysis
Help create, document, maintain and execute experimental protocols (SOPs) and analytical methods to be compatible with Draper's platform technologies
Collect, interpret, summarize, and effectively present data to project team leads, internal management, and external sponsors/customers via presentations and for publication
Work collaboratively with team(s) to execute project plans, and mentor and support colleagues at the bench through teamwork
Troubleshoot experimental work in coordination with colleagues and project leadership
Complete all necessary training, adhere to all laboratory, institutional, and government regulations, and contribute to an environment of safety and compliance
Support business development efforts through technical ideation, proposal writing, and customer outreach as needed
Support lab organization and maintenance as needed, such as sourcing and preparation of reagents and materials

Preferred

PhD in biology or engineering discipline with 0-3 years of post-doctoral or industry experience in a laboratory/R&D setting, or MS in biology or engineering discipline with at least 5 years of industry experience in a laboratory/R&D setting
Experience developing and implementing advanced mammalian tissue models, specifically liver, kidney, immune, neural, or cardiac tissues
Experience with primary mammalian cell and tissue culture, including complex multi-cell type co-cultures, organoid cultures, stem cell or iPSC cultures, and isolating, differentiating, and/or phenotypically and functionally characterizing mammalian cells
Experience with advanced in vitro cell and tissue culture systems, including microfluidic devices, microphysiological systems (MPS), and/or organ-on-chip (OoC) technologies
Experience with a variety of cell and molecular biology assays and methods, such as immunostaining, confocal imaging, image processing, ELISA / Luminex, flow cytometry / FACS, DNA / RNA extraction, qPCR, and multi-omics (e.g. transcriptomics, proteomics, metabolomics), and biostatistical data analyses
Some experience with microbiology (viruses, bacteria, toxins), immunology, synthetic biology, genetic engineering, bioinformatics and data analytics, in silico modeling and / or laboratory automation
Some experience writing innovative R&D proposals for government sponsors (contracts, grants)
Ability to work independently in a collaborative environment and to communicate with engineers, biologists, management, and key stakeholders
Flexibility to multi-task and adapt to changing priorities

Benefits

Workplace flexibility
Employee clubs ranging from photography to yoga
Health and finance workshops
Off site social events
Discounts to local museums and cultural activities

Company

We Engineer Solutions for the Nation’s Toughest Problems As an independent nonprofit engineering innovation company, Draper provides engineering services directly to government, industry, and academia.

Funding

Current Stage
Late Stage

Leadership Team

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Jerry Wohletz
President and Chief Executive Officer
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Brenan McCarragher
Chief Technology Officer
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Company data provided by crunchbase