Twist Bioscience · 23 hours ago
Equipment Engineer
USA - Portland, OR
Full-time
Onsite
Mid Level
3+ years expTwist Bioscience is a company focused on biotechnology, and they are seeking an Equipment Engineer to ensure the reliability and performance of production instrumentation in a DNA synthesis environment. The role involves validating equipment, performing maintenance, troubleshooting issues, and collaborating with other engineers to optimize equipment performance.
B2BBiotechnologyChemicalHealth CareLife Science
Responsibilities
Lead the execution of Installation Qualification (IQ), Operational Qualification (OQ), and Performance Qualification (PQ) for both new and existing instrumentation
Manage the scheduling and execution of routine maintenance and calibrations in strict accordance with manufacturer specifications and internal quality standards
Investigate recurring equipment failures to implement permanent engineering fixes, significantly reducing or eliminating downtime
Utilize and refine equipment risk assessment techniques to prioritize resources and optimize maintenance workflows
Own and ensure the timely closure of equipment-related CAPAs (Corrective and Preventive Actions) and Change Controls
Develop and implement effective Out of Control Action Plans (OCAP) and standard operating procedures
Recommend design modifications or material substitutions to enhance equipment longevity; perform load calculations, voltage studies, and power requirement specifications for small-to-mid-scale projects
Serve as a technical subject matter expert, assisting in the training and development of junior Equipment Engineers
Manage spare parts inventory to ensure immediate availability for critical repairs and implement countermeasures for repetitive part breakdowns
Partner closely with Process Engineers to understand equipment-process interactions and ensure hardware operates within peak specifications
Qualification
Required
BS in Engineering, Physical Sciences, or a related technical discipline
Minimum of 3+ years of professional experience in equipment maintenance, calibration, and repair
Proven ability to design and build projects to improve reliability using mechanical, electrical, and electro-mechanical systems, including PLC programming and control systems
Proficiency in creating layouts, power load drawings, and utility requirement specifications
High attention to detail and strong organizational skills; experience working under ISO 9001, ISO 13485, or GMP/cGMP standards is highly preferred
Ability to multi-task in a dynamic environment and work comfortably in a cleanroom setting (requiring lab coats, hairnets, and gloves)
Excellent interpersonal skills with a collaborative approach to problem-solving
Preferred
Experience working under ISO 9001, ISO 13485, or GMP/cGMP standards is highly preferred
Experience with automated liquid handlers or LIMS integration is a significant plus
Company
Twist Bioscience
Twist Bioscience is a biotechnology company that offers synthetic DNA solutions, gene synthesis, and variant libraries.
501-1000 employees
H1B Sponsorship
Twist Bioscience has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (18)
2024 (14)
2023 (22)
2022 (19)
2021 (4)
2020 (6)
Funding
Current Stage
Public CompanyTotal Funding
$553.11MKey Investors
Capital World InvestorsBiomatics Capital PartnersIllumina
2022-02-09Post Ipo Equity· $250M
2020-01-27Post Ipo Equity· $50M
2018-10-30IPO
Leadership Team
Emily Leproust
CEO
Siyuan Chen
Chief Technology Officer
Recent News
2026-01-07
2025-12-30
Company data provided by crunchbase