Broad Institute of MIT and Harvard · 1 day ago
Computational Associate II - Neurobiology and Therapeutics of Psychiatric Disorders
Cambridge, MA
Full-time
Onsite
Mid Level
$58K/yr - $81K/yr
3+ years expThe Broad Institute of MIT and Harvard is seeking a motivated Computational Associate II to join the Sheng research group in the Stanley Center for Psychiatric Research. This role involves analyzing data from various modalities to uncover neurobiological mechanisms related to psychiatric disorders, collaborating closely with biologists and geneticists.
BiotechnologyClinical TrialsLife Science
Responsibilities
Analyze large RNA-Seq datasets to profile transcriptomes from brain and neuronal cell populations, and interpret results to derive important biological insights into these models
Work with wet-lab biologists to design and implement appropriate experiments for future computational analysis
Provide results in formats accessible to a research community of biologists and geneticists
Develop, apply, document, and maintain computational tools, both for own use and to support analysis by biologist colleagues without formal computational training
Follow relevant scientific literature to ensure use of optimal methods and understand emerging practices across the field
Contribute to reports and papers for presentation and publication and present at scientific conferences, as appropriate
Regularly attend and present results at team meetings to share results, plan projects and experiments
Work with other Broad computational biologists experienced with RNA-Seq, to learn, discuss, and integrate the most appropriate solution for an experiment or project
Qualification
Required
BS with 3+ years of related experience or MS in Bioinformatics, Computer Science, or other relevant scientific discipline with 1+ years of related experience
Experience working with RNAseq data
Should have a demonstrated proficiency in R and/or Python, or related languages
Experience with and solid understanding of statistical analysis is required
Familiarity with next-generation sequence data analysis tools, particularly those for RNA-seq
Familiarity with working on a computing cluster/server (important skills: Unix/Linux, shell scripting)
Ability to work independently as well as part of an interdisciplinary team in a fast-paced environment, while making necessary connections with experts in various computational analysis groups
Self-starter, highly motivated
Excellent organization and time management skills
Preferred
Understanding of molecular biology and next generation sequencing is highly preferred
Familiarity with single cell data analysis is preferred, but not required
Experience designing computational methods and tools, including prior experience with algorithms relevant to computational biology, is a plus
Benefits
Medical, dental, vision, life, and disability insurance
401(k) retirement plan
Flexible spending and health savings accounts
At least 13 paid holidays
Winter closure
Paid time off
Parental and family care leave
Employee assistance program
Company
Broad Institute of MIT and Harvard
The Broad Institute brings together a diverse group of individuals from across its partner institutions — undergraduate and graduate students, postdoctoral fellows, professional scientists, administrative professionals, and academic faculty.
1001-5000 employees
H1B Sponsorship
Broad Institute of MIT and Harvard has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
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Trends of Total Sponsorships
2025 (108)
2024 (59)
2023 (73)
2022 (68)
2021 (70)
2020 (93)
Funding
Current Stage
Late StageTotal Funding
$283.25MKey Investors
MacArthur FoundationAlzheimer's Foundation of AmericaMassachusetts Life Sciences Center
2025-11-18Grant· $100M
2020-08-11Grant
2019-09-09Grant· $0.75M
Leadership Team
Dan Shore
Chief Financial Officer
Anne Carpenter
Institute Scientist and Imaging Platform Senior Director
Recent News
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