Pfizer · 1 day ago
Principal Scientist - Process Analytical Technology
Michigan, United States
Full-time
Onsite
Senior Level, Lead/Staff
$99K/yr - $160K/yr
2+ years expPfizer is a leading pharmaceutical company dedicated to advancing health. They are seeking a Principal Scientist to implement process analytical technology (PAT) in support of manufacturing operations, focusing on enhancing process performance and knowledge through advanced analytical and data science skills.
BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
No H1B
U.S. Citizen Only
Responsibilities
Implement technical solutions and analytical strategies using PAT
Lead adoption and use of PAT instruments and machine learning models
Assess feasibility and ensure technical soundness of instruments/models for process monitoring and control
Apply scientific concepts across chemistry, PAT, and data science with high learning agility
Support automation development between PAT tools and process data systems (e.g., AVEVA Pi)
Mentor and develop scientific staff; promote growth and knowledge sharing
Plan and manage short- and long-term development activities, timelines, and resource allocation
Foster diverse perspectives to drive innovative solutions
Coordinate instrumentation usage across projects for equitable access
Contribute to technical documentation (SOPs, tech transfer, process diagrams, regulatory submissions)
Ensure compliance with development quality, regulatory, HSE, GLP, and GMP requirements
Qualification
Required
Applicant must have a bachelor's degree with at least 4 years of experience; OR a master's degree with at least 2 years of experience; OR a PhD with 0+ years of experience; OR as associate's degree with 8 years of experience; OR a high school diploma (or equivalent) and 10 years of relevant experience
Work effectively in a fast-paced, customer-oriented, laboratory/production environment to implement process analytical technology (PAT) that supports Active Pharmaceutical Ingredient (API) and Drug Product (DP) Manufacturing Operations
Identify, develop, and deliver PAT applications in support of commercial manufacturing
Support the Process Analytical Technology (PAT) program and the Operational Excellence initiatives utilizing advanced analytical, chemometric, and data science skills to upgrade process performance and/or increase process knowledge
Support product transfers, new product development, and cost improvement projects
Implement technical solutions and analytical strategies using PAT
Lead adoption and use of PAT instruments and machine learning models
Assess feasibility and ensure technical soundness of instruments/models for process monitoring and control
Apply scientific concepts across chemistry, PAT, and data science with high learning agility
Support automation development between PAT tools and process data systems (e.g., AVEVA Pi)
Mentor and develop scientific staff; promote growth and knowledge sharing
Plan and manage short- and long-term development activities, timelines, and resource allocation
Foster diverse perspectives to drive innovative solutions
Coordinate instrumentation usage across projects for equitable access
Contribute to technical documentation (SOPs, tech transfer, process diagrams, regulatory submissions)
Ensure compliance with development quality, regulatory, HSE, GLP, and GMP requirements
Preferred
Minimum 3 years with production applicable PAT experience is preferred
Broad spectroscopy background preferred with the ability to perform multi-variate data analysis
Demonstrated ability to program in R, Python, and/or MATLAB is preferred
Benefits
Participation in Pfizer’s Global Performance Plan with a bonus target of 12.5% of the base salary
Eligibility to participate in our share based long term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage
Company
Pfizer
Pfizer is a biopharmaceutical company that discovers, develops, and delivers medicines and vaccines.
10001+ employees
Funding
Current Stage
Public CompanyTotal Funding
$38BKey Investors
Starboard Value
2025-11-21Post Ipo Debt· $6B
2024-10-07Post Ipo Equity· $1B
2023-05-16Post Ipo Debt· $31B
Leadership Team
Albert Bourla
Chief Executive Officer
Ian Read
Chief Executive Officer
Recent News
2026-01-08
Company data provided by crunchbase