Alexion Pharmaceuticals, Inc. · 16 hours ago
Clinical Pharmacology Intern (PhD)
Gaithersburg, Maryland, United States of America
Internship
Onsite
Intern
$48/hr - $48/hr
Start in 2026 SpringAlexion Pharmaceuticals, Inc. is seeking PhD students for a 12-week internship in Clinical Pharmacology. The role involves conducting systematic literature reviews, data extraction and curation, critical appraisal, and manuscript preparation.
BiotechnologyHealth CareMedicalTherapeutics
No H1B
Responsibilities
Systematic Literature Review: Define search strategies, inclusion/exclusion criteria, and screen abstracts/full texts to identify studies on pharmacokinetics, pharmacodynamics, pharmacogenomics, and clinical response differences between Chinese and Caucasian populations
Data Extraction and Curation: Extract quantitative parameters (e.g., clearance, volume of distribution, bioavailability, half-life, exposure metrics like AUC/Cmax) and qualitative factors (e.g., allele frequencies for CYPs/UGTs/transporters, diet, BMI, co-medications), ensuring standardized units, metadata, and traceability
Critical appraisal and bias assessment: Evaluate study quality, population characteristics, analytical methods, and confounders; document heterogeneity and risk of bias to inform modeling assumptions
Manuscript preparation: Draft manuscript/conference abstract/poster
Qualification
Required
PhD students studying Clinical Pharmacology, Pharmacokinetics, Pharmaceutics, Pharmaceutical Sciences, PK/PD, DMPK or a related discipline
Candidates must have an expected graduation date after August 2026
Knowledge of pharmacokinetics, drug metabolism, drug transporter, and clinical pharmacology are required
US Work Authorization is required at time of application
Ability to report onsite to Gaithersburg, MD site 3-5 days per week. This role will not provide relocation assistance
Preferred
Experience with clinical trial design and clinical study are preferred
Knowledge of PBPK is a plus
Enthusiasm for collaboration, cross-functional projects, public speaking, and presentation design
Benefits
Short-term incentive bonus opportunity
Equity-based long-term incentive program (salaried roles)
Retirement contribution (hourly roles)
Commission payment eligibility (sales roles)
Qualified retirement program [401(k) plan]
Paid vacation and holidays
Paid leaves
Health benefits including medical, prescription drug, dental, and vision coverage
Company
Alexion Pharmaceuticals, Inc.
Alexion, AstraZeneca Rare Disease is focused on pioneering new possibilities for the rare disease community.
Founded in 1992
1001-5000 employees
Funding
Current Stage
Public CompanyTotal Funding
$5.8M2020-12-12Acquired
1999-02-12Post Ipo Equity· $5.8M
1996-02-29IPO
Leadership Team
Frederic Chereau
SVP, Strategy and Business Development
Imran Shakur
Director, IRT and Technology Lead
Recent News
bloomberglaw.com
2025-12-20
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