Roche · 1 day ago
Principal Product Leader, Core Lab Workflows
South San Francisco
Full-time
Hybrid
Lead/Staff
$149K/yr - $276K/yr
8+ years expRoche is a company dedicated to advancing science and ensuring healthcare access for all. The Principal Product Leader will define and execute the strategy for core lab workflows, focusing on the end-to-end lifecycle of core lab services to enhance scientific research and operational efficiency.
BiotechnologyHealth CareHealth DiagnosticsOncologyPharmaceuticalPrecision Medicine
Responsibilities
Own the product strategy and roadmap for the Core Lab Workflows product family, covering assay/service request intake, experiment orchestration, scheduling and capacity management, and work assignment across core labs
Partner with core lab scientific and operational leadership to translate assay requirements, fitness-for-purpose criteria, and experimental variables into structured, validated requests and executable workflows
Design and evolve intelligent intake experiences that ensure completeness of requests upfront, accounting for required metadata, sample readiness, inventory availability, and automation or instrument constraints
Lead the evolution of the end-to-end sample and material lifecycle, including accessioning, derivations and aliquots, chain-of-custody, storage, transfers, and disposition, with complete provenance and persistent identifiers (GUPRIs)
Improve LIMS/LES usability and effectiveness for bench scientists and core lab staff by streamlining task flows, reducing manual entry, and supporting instrument-adjacent and automation-aware execution
Ensure seamless integration with ELN (protocols and versions), master data and registries, vocabularies and ontologies, lab automation, and downstream analysis pipelines, stewarding consistent APIs, events, and versioned data contracts
Lead cross-functional teams (engineering, UX, scientific SMEs, analysts) through discovery, delivery, and adoption with clear OKRs, release planning, and change management in partnership with RDE Office and OCM
Manage stakeholder alignment, risks, and dependencies across research, informatics, and operations, maintaining a balanced backlog across near-term lab needs and foundational platform capabilities
Ensure solutions meet Roche standards for data quality, access control, security, compliance, and validation in a regulated research environment
Build strong partnerships across the Computational Sciences CoE and with external vendors and collaborators supporting core lab technologies
Qualification
Required
8+ years of experience in product management or adjacent roles delivering software that supports research labs or core facilities (e.g., LIMS/LES, assay request systems, scheduling/capacity, sample management, or lab automation)
Deep understanding of core lab operating models and end-to-end lab services—from request intake and experiment planning through execution and results delivery
Demonstrated expertise in assay metadata, experimental context capture, and sample provenance, with hands-on experience integrating ELNs, registries/master data (e.g., GUPRIs), instruments, automation, and analysis pipelines
Strong fluency in data models, APIs/events, data contracts, validation and quality practices, and change control in complex scientific environments
Proven ability to translate scientific and operational needs into clear product strategy, roadmaps, and measurable outcomes, with strong stakeholder communication and executive presence
A user-centric mindset, with evidence of improving UX in complex, high-throughput lab workflows using data and telemetry to drive iteration
Bachelor's degree in life sciences, engineering, or a related field; advanced degree or direct lab/core facility experience is strongly preferred
Benefits
Relocation benefits are available for this job posting.
A discretionary annual bonus may be available based on individual and Company performance.
Company
Roche
Roche is a pharmaceutical and diagnostics company that offers medicines and diagnostic tests for various medical conditions and diseases.
10001+ employees
H1B Sponsorship
Roche has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (12)
2024 (9)
2023 (6)
2022 (2)
2021 (2)
Funding
Current Stage
Public CompanyTotal Funding
$7.79BKey Investors
SoftBankSCALE AINovartis
2021-08-04Post Ipo Equity· $5B
2020-12-07IPO
2020-05-06Post Ipo Equity· $0.5M
Leadership Team
Alan Hippe
Member of the Executive Board - Group CFO
Christine Bakan
Global Head and VP of Software and Bioinformatics, Next Generation Sequencing
Recent News
2026-01-09
2026-01-07
Company data provided by crunchbase