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UW School of Medicine and Public Health · 2 days ago

Tissue Autoradiography Scientist

Madison, WI

Full-time

Onsite

Mid, Senior Level

2+ years exp

The UW School of Medicine and Public Health is seeking a Tissue Autoradiography Scientist to contribute to the discovery and development of novel PET imaging tracers. The successful candidate will lead various tissue-based assays and collaborate on improving early diagnosis and therapeutic development in neurodegenerative diseases.

EducationHealth CareHigher EducationUniversities

No H1B

U.S. Citizen Only

Responsibilities

Conducts literature reviews, prepares reports and materials, and disseminates information to appropriate entities

Serves as a main point of contact and liaison with internal and external stakeholders providing information and representing the interests of a specialized research area

Assists with the identification of research problems and the development of research methodologies and procedures

Attends and assists with the facilitation of scholarly events and presentations in support of continued professional development and the dissemination of research information

Assists with ordering, tracking, and maintenance of lab instruments and radiolabeled compounds; ensuring appropriate safety, documentation and regulatory compliance (e.g., EH&S, ORS)

Collects and analyzes research data, conducts experiments and interviews, and documents results according to established policies and procedures under general supervision and limited responsibility

Contributes to invention disclosures and intellectual property documentation related to new imaging agents

Writes or assists in developing grant applications and proposals to secure research funding

Qualification

Tissue assay developmentAutoradiographyRadioligand binding assaysSurface Plasmon ResonanceBiochemical extractionHistopathological techniquesCollaborative researchTroubleshooting experimental systemsScientific rigorCommunication

Required

A minimum of 2 years of post-doctoral experience or equivalent industry experience

PhD Degree required; focus in bioanalytical science, biochemistry, molecular biology or a related field required

Preferred

Advanced experience in tissue-based assay development, including autoradiography and radioligand binding assays using both tissue slices and purified proteins

Proficiency in biochemical extraction and purification of pathological proteins (e.g., α-synuclein, tau) from human and animal brain tissue

Demonstrated ability to perform competitive binding and displacement assays to quantify tracer specificity and affinity

Experience conducting Surface Plasmon Resonance (SPR) experiments or related biophysical assays for assessing molecular interactions

Familiarity with histopathological techniques, including immunostaining and tissue sectioning for quantitative analysis

Strong record of collaborative research in interdisciplinary, multi-site translational programs

Ability to independently troubleshoot complex experimental systems and contribute to project design

Commitment to maintaining high standards of scientific rigor, data documentation, and reproducibility

Excellent communication skills and the ability to work effectively in a collegial academic research environment

Benefits

Generous vacation, holidays, and sick leave

Competitive insurances and savings accounts

Retirement benefits

Company

UW School of Medicine and Public Health

UW School of Medicine and Public Health offers graduate programs, health professions programs, and innovative research. It is a sub-organization of University of Wisconsin-Madison.

Founded in 1907

Madison, Wisconsin, USA

5001-10000 employees