BioMarin Pharmaceutical Inc. · 2 weeks ago
Scientist II, Analytical Pathology, Enzymes and Metabolic Research Unit
San Rafael, CA
Full-time
Onsite
Mid, Senior Level
3+ years expBioMarin Pharmaceutical Inc. is a global biotechnology company focused on developing transformative medicines for genetic conditions. They are seeking a highly motivated Scientist II to conduct preclinical translational research and evaluate potential therapeutics for severe rare genetic diseases, utilizing advanced histological techniques and image analysis.
BiotechnologyDeveloper PlatformPharmaceutical
Responsibilities
Strong understanding and hands-on experience of histological techniques, including but not limited to, immunohistochemistry, in situ hybridization and spatial transcriptomics
Advanced microscopy and imaging skills including multiplex fluorescence imaging, confocal microscopy, live-cell imaging, laser capture microdissection, light-sheet microscopy
Develop novel image analysis algorithms using advanced image analysis software to quantify markers of pathology, subcellur localization and/or biodistribution of novel drug candidates
Lead or provide functional support for early stage project teams from exploratory through Stage -1
Author study plans, protocols, technical reports, and SOPs associated with the research design and methods developed to investigate the mechanism of action, efficacy, quality or safety of novel drug candidates
Collaborate with Business Development on efforts to identify and nominate new assets for investigation and acquisition
Mentor and coach junior staff on experimental design, troubleshooting, assay optimization and data interpretation
Qualification
Required
PhD with a minimum of 3-5 years related or post-doctoral experience; or a MS and a minimum of 8-10 years related experience; or a BA/BS and a minimum of 8-15 years related experience
Strong understanding and hands-on experience of histological techniques, including but not limited to, immunohistochemistry, in situ hybridization and spatial transcriptomics
Advanced microscopy and imaging skills including multiplex fluorescence imaging, confocal microscopy, live-cell imaging, laser capture microdissection, light-sheet microscopy
Develop novel image analysis algorithms using advanced image analysis software to quantify markers of pathology, subcellular localization and/or biodistribution of novel drug candidates
Lead or provide functional support for early stage project teams from exploratory through Stage -1
Author study plans, protocols, technical reports, and SOPs associated with the research design and methods developed to investigate the mechanism of action, efficacy, quality or safety of novel drug candidates
Collaborate with Business Development on efforts to identify and nominate new assets for investigation and acquisition
Mentor and coach junior staff on experimental design, troubleshooting, assay optimization and data interpretation
Strong background in analytical pathology, histological techniques, database management and image analysis platforms
Knowledge of project management tools, methodologies and best practices
Excellent CRO management, budgeting and resource allocation skills
Demonstrated ability to work in a fast-paced, team-orientated environment with aggressive timelines
Ability to interact successfully with team members from a wide variety of functional areas and all levels of contribution and expertise
Strong communication (verbal and written) skills
Preferred
Background in enzyme replacement therapies, lysosomal storage disorders or rare genetic metabolic disease
Company
BioMarin Pharmaceutical Inc.
Founded in 1997, BioMarin is a global biotechnology company dedicated to transforming lives through genetic discovery.
1001-5000 employees
H1B Sponsorship
BioMarin Pharmaceutical Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (34)
2024 (23)
2023 (24)
2022 (26)
2021 (24)
2020 (19)
Funding
Current Stage
Public CompanyTotal Funding
$585.8M2020-05-11Post Ipo Debt· $585.8M
1999-07-26IPO
Leadership Team
Brian Mueller
Chief Financial Officer
Cristin Hubbard
Chief Commercial Officer
Recent News
Morningstar.com
2026-01-09
Company data provided by crunchbase