Animerra · 1 day ago
Associate Scientist / Scientist - Biologics
Greater Boston
Full-time
Onsite
Mid, Senior Level
2+ years expAnimerra is a second-generation antibody discovery company focused on companion animal therapeutics. They are seeking a highly motivated RA/Scientist to advance the company’s therapeutic portfolio with a focus on antibody discovery and engineering, utilizing molecular biology techniques and protein engineering.
BiotechnologyPharmaceuticalVeterinary
Responsibilities
Design and execute molecular cloning strategies including vector construction, site-directed mutagenesis, PCR, DNA assembly (e.g., Gibson, Golden Gate), DNA purification and sequence analysis
Use display screening to select and optimize antibody products
Express and purify recombinant proteins using bacterial, yeast, and/or mammalian expression systems
Purify proteins using techniques such as ion exchange, tagged based purifications, SEC, reverse phase
Characterize proteins using techniques such as SDS-PAGE, Western blot, size-exclusion chromatography, thermal shift, and binding assays (e.g., ELISA, SPR, BLI)
Maintain detailed records of experimental design, results, and protocols in electronic lab notebooks (ELNs)
Analyze data and contribute to the interpretation and presentation of results in internal meetings and external reports
Collaborate with cross-functional team to achieve goals and assist with various projects
Qualification
Required
Master's degree or PhD in Molecular Biology, Biochemistry, Protein Engineering, or related discipline with 2–5+ years of industry lab experience. Job title commensurate with experience
Hands-on experience with standard molecular biology techniques (e.g., PCR, plasmid design, gel electrophoresis)
Experience with protein display techniques (e.g., phage display, yeast display, mRNA display)
Strong background in heterologous protein expression and purification workflows
Experience with engineering and expressing antibodies and/or antibody derived proteins
Familiarity with sequence analysis tools (e.g., SnapGene, BLAST)
Proficient in data analysis and visualization (e.g., GraphPad Prism, Excel, R or Python a plus)
Excellent organizational, communication, and teamwork skills
Preferred
Experience with high-throughput cloning or protein expression
Knowledge of structural biology and protein modeling tools (e.g., PyMOL, AlphaFold) is a bonus
Experience with NGS sequencing and/or bioinformatics of antibodies
Experience working within a small, dynamic team
Experience working in a fast-paced environment
Company
Animerra
Animerra is a healthcare company.
2-10 employees
Funding
Current Stage
Early StageTotal Funding
$6.5M2025-02-03Seed· $6.5M
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