Biogen · 12 hours ago
Principal Scientist, Immunology
San Francisco, CA
Full-time
Onsite
Senior Level, Lead/Staff
$142K/yr - $190K/yr
5+ years expBiogen is a mid-sized biotechnology company dedicated to delivering life-changing medicines. They are seeking a highly motivated Principal Scientist in Immunology to lead innovative studies in drug discovery and development for inflammatory and autoimmune disorders, contributing to the advancement of novel therapies.
BiotechnologyHealth CareNeuroscienceTherapeutics
Responsibilities
Design and lead innovative in vitro and in vivo studies to uncover mechanisms driving inflammatory and autoimmune diseases
Discover and validate novel drug targets, biomarkers, and pathways critical to immune-mediated disorders
Deliver high-quality data to support lead optimization, biomarker development, and translational research for priority programs in our expanding Immunology pipeline
Analyze and interpret complex datasets, ensuring scientific rigor, reproducibility, and adherence to regulatory and safety standards; communicate findings through internal presentations and external forums (conferences, publications)
Collaborate across disciplines—including pharmacology, synthetic medicine, protein engineering, and computational sciences—to advance target identification, drug discovery, and clinical development
Shape portfolio strategy by identifying gaps and opportunities for scientific innovation
Partner with business development and corporate strategy teams to evaluate the scientific merit of potential assets, collaborations, and licensing opportunities
Contribute to due diligence efforts, including mechanistic evaluations, protocol reviews, external data assessments, and intellectual property analysis
Champion scientific excellence and innovation by staying current with emerging research and technologies in immunology and inflammation
Qualification
Required
PhD in Immunology, Cellular and Molecular Biology, or a related scientific field with 5+ years of industry experience, preferably in inflammatory and autoimmune disease drug discovery and development (Masters with 8+ years of experience, Bachelors with 10+ years of experience)
Strong expertise in immune cell biology (innate and adaptive immunity), cell signaling, and immunological assay development
Hands-on experience with relevant techniques, including, biochemical and cellular assay development, tissue culture, flow cytometry, and functional genomics techniques
Experience with disease models of inflammation and/or autoimmunity
Ability to manage multiple priorities in a fast-paced environment
Strong problem-solving skills and ability to work independently and in team settings
Collaborative mindset with strong interpersonal skills
Strong analytical skills for evaluating scientific data and external opportunities
Excellent communication skills for translating complex science into business-relevant insights
Preferred
Prior experience in biotech/pharma drug discovery or translational research (5+ years)
Experience working with small molecule, biologics, and/or cell based therapeutic drug discovery and development
Strong technical expertise in multiparametric flow cytometry (e.g. 15+ colors)
Experience with multiomics analyses (e.g. genomic, transcriptomic, proteomics, etc.)
Experience in due diligence and business development support is highly desirable
Benefits
Medical, Dental, Vision, & Life insurances
Fitness & Wellness programs including a fitness reimbursement
Short- and Long-Term Disability insurance
A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
Up to 12 company paid holidays + 3 paid days off for Personal Significance
80 hours of sick time per calendar year
Paid Maternity and Parental Leave benefit
401(k) program participation with company matched contributions
Employee stock purchase plan
Tuition reimbursement of up to $10,000 per calendar year
Employee Resource Groups participation
Company
Biogen
Biogen is an American biotechnology company that provides therapeutics for neurological, autoimmune, and rare diseases.
Founded in 1978Cambridge, Massachusetts, USA
5001-10000 employees
H1B Sponsorship
Biogen has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (100)
2024 (93)
2023 (101)
2022 (134)
2021 (104)
2020 (114)
Funding
Current Stage
Public CompanyTotal Funding
$1.5BKey Investors
JP Morgan
2023-08-28Post Ipo Debt· $1.5B
1991-09-27IPO
Leadership Team
Robin C. Kramer
Executive Vice President, Chief Financial Officer
Priya Singhal
Executive Vice President, Head of Development
Recent News
Pharmaceutical Technology
2026-01-05
thecanadianpressnews.ca
2025-12-24
Company data provided by crunchbase