Oxford BioTherapeutics · 1 day ago
Senior RA/Associate Scientist
San Jose, CA
Full-time
Onsite
Senior Level
5+ years expOxford Biotherapeutics (OBT) is a clinical-stage biotechnology company developing innovative antibody-based therapeutics for the treatment of cancer. The Antibody Discovery Research Associate will support early-stage therapeutic and tool antibody programs by performing experiments that contribute to antibody generation using single B cell platforms, screening, and lead candidate selection.
BiotechnologyGeneticsHealth CareHealth DiagnosticsTherapeutics
Hiring Manager
Almudena Heredia Usero
Responsibilities
Perform hands on antibody discovery work flows including cell culture, multi colour flow cytometry to sort and analyse rare immune cell populations
Develop, optimize and perform screening cell-based functional assays
Characterize antibodies by performing Elisa, SPR, BLI (Octet), Western blot
Maintenance of cell lines, freezing, thawing, expansion
Perform molecular biology tasks like PCR, cloning, transfection, sequence analysis, RNA/DNA purification methods, gel extraction as needed
Ensure all experimental work complies with established protocols and SOP’s
Maintain accurate and detailed experimental records and record all experimental data into Electronic Notebook
Contribute to troubleshooting, optimization, and continuous improvement of discovery workflows
Compiling and analysing data by FlowJo, GraphPad Prism, and Excel
Conduct analysis and effectively communicate results and present data at internal meetings
Collaborate with cross functional teams to align with project goals
Committed to fostering an inclusive, collaborative, and innovative research environment
Qualification
Required
S. or M.S. in Molecular Biology, Immunology, Bioengineering, Biochemistry, or related field with 5+ years of experience working in a lab setting (industry experience preferred)
Experience with antibody discovery platforms including single B cell, hybridoma, or display technologies
Proficiency in mammalian cell culture, in vitro assay development and flow cytometry
Strong organizational skills, attention to detail and ability to work independently and collaboratively
The ability to be a team player and collaborate with colleagues is critical
Preferred
Strong understanding of B cell biology
Experience working with antibody sequences, including CDR identification and diversity analysis
Hands-on experience with multi-color flow cytometry including panel design, staining, compensation, and data analysis/interpretation
Hands on experience with BLI or SPR
Assay development and characterising antibodies using cell-based assays and flow cytometry
Comfortable working with high-throughput screening tools or automation
Experience with cell engineering technologies, such as transfection, electroporation, lentiviral transduction, and CRISPR
Experience with high-throughput antibody expression & purification
Experience with cytotoxicity assays using T cell engagers
Innovative, detail-oriented, and quality-driven with a proactive mindset
Exceptional communication and interpersonal skills; able to translate complex data for diverse audiences
Highly motivated self-starter with scientific curiosity and a roll-up-your-sleeves attitude
Flexible and eager to learn new methods and optimize workflows
Benefits
Medical, dental, and vision insurance for employees and dependents
Flexible Spending Account (FSA)
Short‑Term Disability (STD), Long‑Term Disability (LTD), Basic Life & AD&D, and Supplemental Life insurance
401(k) plan
120 hours of Paid Time Off + 5 sick days per year
11 public holidays
Annual bonus program
Employee referral bonus program
New hire stock options
Company
Oxford BioTherapeutics
Oxford BioTherapeutics develops medicines for cancer and companion diagnostics for selected antibody programs.
11-50 employees
H1B Sponsorship
Oxford BioTherapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2020 (1)
Funding
Current Stage
Early StageTotal Funding
$33.22MKey Investors
Calculus CapitalOxford Finance LLCSilicon Valley Bank
2021-01-01Series Unknown
2018-08-03Series Unknown· $2.6M
2017-01-26Debt Financing· $10M
Leadership Team
Abderrahim Fandi, MD PhD
Chief Medical Officer
Joyce B.
Human Resources and Office Business Partner
Recent News
2025-12-15
MarketScreener
2025-12-10
Company data provided by crunchbase