Roche · 17 hours ago
2026 Summer Intern - Computational Sciences CoE - Computational Biology and Medicine
South San Francisco
Internship
Onsite
Intern
$50/hr - $50/hr
Start in 2026 SpringRoche is a leading biotechnology company that focuses on transforming drug discovery and development through AI and computational sciences. They are seeking a Summer Intern for their Computational Sciences Center of Excellence to lead impactful projects involving single-cell RNA-seq data and large language models.
BiotechnologyHealth CareHealth DiagnosticsOncologyPharmaceuticalPrecision Medicine
Responsibilities
Lead the development of a Transformer-based Language Model using the Cell to Sentence or similar frameworks to learn robust cell representations
Aggregate, clean, and integrate large single-cell RNA-seq datasets
Apply the trained LLM to fine-tune tasks, such as predicting phenotype shifts
Work closely with established computational scientists to drive computational research in the pre-clinical
Qualification
Required
Must be pursuing a PhD (enrolled student)
Required majors: Computational Biology, Bioinformatics, Computer Sciences, or a related field
Proficiency in Python and PyTorch
Track record of developing or applying deep generative models and machine learning techniques to capture robust cell representations and perform dataset integration
Conceptual understanding of transformer architecture and practical experience with self-supervised objectives for sequence data
Expert proficiency with the single-cell ecosystem, including scanpy and working with large-scale AnnData objects
Track record of working with single-cell RNA-sequencing data and application of machine learning techniques to cell representations. This includes, but is not limited to, knowledge of single-cell data processing methods and dataset integration, and machine learning methods to capture cell representations
Experience working with Git for version control and utilizing High-Performance Computing (HPC) resources
Preferred
Knowledge of T cell biology and experience working with TCR sequencing data is a plus
Excellent communication, collaboration, and interpersonal skills
Detail-oriented, goal-driven, and dedicated to delivering high-quality results
Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion
Benefits
Paid holiday time off benefits
Company
Roche
Roche is a pharmaceutical and diagnostics company that offers medicines and diagnostic tests for various medical conditions and diseases.
Founded in 1896
10001+ employees
H1B Sponsorship
Roche has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
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Trends of Total Sponsorships
2025 (12)
2024 (9)
2023 (6)
2022 (2)
2021 (2)
Funding
Current Stage
Public CompanyTotal Funding
$7.79BKey Investors
SoftBankSCALE AINovartis
2021-08-04Post Ipo Equity· $5B
2020-12-07IPO
2020-05-06Post Ipo Equity· $0.5M
Leadership Team
Alan Hippe
Member of the Executive Board - Group CFO
Christine Bakan
Global Head and VP of Software and Bioinformatics, Next Generation Sequencing
Recent News
2026-01-07
2026-01-07
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