Plexus Partners · 1 day ago
Oncology Principal Investigator
Los Angeles County, CA
Full-time
Onsite
Senior Level, Lead/Staff
1+ years expPlexus Partners is representing a research-focused oncology organization seeking a Principal Investigator to oversee a clinical team and drive breakthrough studies with biotech sponsors. The role involves leading oncology trials, ensuring patient safety, and collaborating with various stakeholders in a fast-growing clinical environment.
Staffing & Recruiting
Hiring Manager
Elliot Stocks
Responsibilities
Serve as the Principal Investigator for oncology trials across multiple modalities and sponsors
Provide medical oversight, ensure patient safety, and maintain protocol compliance and data integrity
Supervise and mentor sub-investigators, nurse practitioners, and clinical operations staff
Collaborate closely with sponsors, CROs, and internal study teams to drive enrollment and site performance
Support scientific and operational strategy, SOP refinement, and future site development
Participate in investigator meetings, safety reviews, and regulatory inspections
Qualification
Required
MD or DO with board certification or eligibility in Hematology/Oncology (or related discipline)
Licensed or license-eligible to practice medicine in California
1–5+ years post-fellowship experience (early-career attendings encouraged to apply)
Demonstrated clinical excellence and the ability to manage oncology patients in a research setting
Strong communication skills, collaborative mindset, and enthusiasm for research and innovation
Must be committed to a full-time, on-site position
Preferred
Prior Sub-I or PI experience preferred but not required — full GCP training and mentorship provided
Benefits
Competitive Compensation
Relocation and performance incentives
Company
Plexus Partners
We connect life science innovators to the people they can’t reach, through networks we’ve spent years building.
2-10 employees
Funding
Current Stage
Early StageCompany data provided by crunchbase