Technical Program Manager – AI/ML Initiatives jobs in United States
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McKesson · 11 hours ago

Technical Program Manager – AI/ML Initiatives

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. The Technical Program Manager will lead enterprise-scale AI/ML programs by defining strategic roadmaps, orchestrating cross-functional collaboration, and ensuring delivery excellence while driving innovation and maintaining compliance and governance standards.

BiopharmaBiotechnologyHealth CareInformation TechnologyPharmaceutical
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H1B Sponsor Likelynote

Responsibilities

Define and own the end-to-end roadmap for AI/ML initiatives, translating business objectives into actionable programs (e.g., demand forecasting models, LLM-driven chatbots, predictive analytics). Manage intake of new requests, validate business value, and ensure alignment with strategic priorities. Use portfolio tools (Jira, Confluence, MS Project, Smartsheet) to maintain visibility and alignment from ideation through deployment
Coordinate collaboration among data scientists, ML engineers, data engineers, business analysts, and IT teams. Ensure seamless integration of models into production systems via APIs, cloud ML services, and CI/CD pipelines
Oversee day-to-day delivery using Agile practices (Scrum, SAFe, Kanban). Manage sprints, backlogs, and dependencies in Jira/Confluence. Identify risks (data gaps, performance issues, infrastructure bottlenecks) and implement mitigation strategies. Enforce testing standards (unit tests, model validation, A/B testing, benchmarking)
Translate business use cases into technical AI/ML requirements. Partner with leaders to define KPIs (accuracy, ROI, adoption). Provide executive-level updates and manage expectations while balancing speed, compliance, and ethics
Ensure adherence to frameworks (HIPAA, GDPR, SOC 2, FDA). Promote Responsible AI principles (fairness, transparency, explainability). Maintain documentation, data lineage, and reproducibility. Standardize MLOps governance (model versioning, drift monitoring, automated retraining)
Define and track KPIs across technical and business dimensions (accuracy, precision/recall, F1 score, ROI, cost reduction). Provide transparent reporting on portfolio health and program success
Drive adoption of emerging technologies (Generative AI, LLMOps, AutoML). Collaborate on modernizing ML stack (Databricks, Vertex AI, Azure ML). Promote accelerators (code libraries, pre-trained models, standardized pipelines) to reduce time-to-market

Qualification

Technical Program ManagementAI/ML TechnologiesAgile MethodologiesMLOps PracticesCloud PlatformsRegulatory ComplianceGenerative AIStakeholder ManagementRisk ManagementCommunication Skills

Required

Proven experience in technical program management for AI/ML initiatives
Strong understanding of Agile methodologies and portfolio management tools
Expertise in AI/ML technologies, MLOps practices, and cloud platforms
Ability to translate business objectives into technical deliverables
Excellent stakeholder management and communication skills
Degree or equivalent and typically requires 10+ years of relevant experience. Less years required if has relevant Master's or Doctorate qualifications

Preferred

Familiarity with regulatory compliance for AI/ML (HIPAA, GDPR)
Experience with Generative AI, LLMOps, and AutoML
Knowledge of advanced ML platforms (Databricks, Azure ML, Vertex AI)
Strong background in risk management and governance for AI systems

Benefits

Competitive compensation package
Annual bonus
Long-term incentive opportunities

Company

McKesson

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McKesson distributes medical supplies, information technology, and care management products and services.

H1B Sponsorship

McKesson has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (149)
2024 (129)
2023 (82)
2022 (142)
2021 (144)
2020 (154)

Funding

Current Stage
Public Company
Total Funding
unknown
1994-11-18IPO

Leadership Team

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Brian Tyler
CEO
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Jim McAuliffe
CFO
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Company data provided by crunchbase