insitro · 1 day ago
(Senior) Director, Project Team Lead - Clinical
South San Francisco, CA
Full-time
Hybrid
Senior Level, Lead/Staff, Director/Executive
$210K/yr - $275K/yr
8+ years expinsitro is using machine learning to yield new, clinically actionable insights into critical unmet needs for patients. The Senior Director, Project Team Lead for Clinical Development will lead cross-functional drug development teams from preclinical development candidate nomination through Phase 1-2 clinical development, ensuring effective integration of therapeutic strategies and risk mitigation.
BiotechnologyHealth CareLife ScienceMachine LearningPharmaceuticalTherapeutics
Responsibilities
In collaboration with cross-functional teams and working closely with Project and Portfolio Management:
Cross-functional asset/program leadership is the key part of this role
Develop and implement clinical program plans
Develop vision, strategy, and an end-to-end product plan that accounts for early uncertainties in first-in-human clinical development, define prospective, quantifiable endpoints for effective Go No Go decisions, enable the generation of a clinical data package that could support future registrational trial development and commercialization, and ensure there are adequate resources and technical expertise to meet strategic objectives
Identify and manage critical path activities and resources
Identify and manage interdependencies and hand-offs
Identify, classify, proactively mitigate, and document (as appropriate) potential risks and roadblocks, including likelihoods, severities, and key mitigations
Lead contingency planning
Capture and communicate progress; escalate potential delays with proposed solutions
Direct clinical programs through insitro governance to ensure that:
Key drug development functions including preclinical, clinical, technical development/CMC and computational achieve strategic and operational alignment
Programs have adequate resources and technical expertise to meet strategic objectives
Issues are raised, discussed, and resolved in a timely manner
Program/project teams receive insitro Governance decisions in a timely manner
Programs adhere to agreed-upon scope, timelines, resources, and budget
Communication and Culture
Accountable for clear and timely communication about the program throughout insitro such as via: agendas, minutes, all-hands and other communication methods
Responsible for facilitating Core Team meetings and working with Sub-team Leaders to ensure sub-teams and Core Teams are working in alignment on strategic and operational topics
Present project updates, strategic issues, options, and recommendations to the insitro Governance Committees
Ensure clear and effective communication by each asset/project team by overseeing/reviewing presentations and documents to ensure clarity and effectiveness
Contribute to team culture and positively influence team environment that encourages authentic, clear communication and a 'get stuff done' mentality
Qualification
Required
PhD or MD with 8 (Director) or 12+ (senior director) years (including doctoral or MD experience) of relevant experience and/or advanced education in life sciences, health-related field, or equivalent practical experience
5+ years of experience in clinical project/asset team leadership or equivalent role in biotechnology and/or pharmaceutical industries, directly as a PTL and in a leadership/management role to deliver therapeutic(s) and diagnostic biomarker(s) in at least one of our key therapeutic areas (metabolic disease, neurology/neurodegeneration, oncology) from FIH through proof-of-concept in the clinic to transition to late development to NDA/BLA submission
Capable of communicating and collaborating with people of diverse backgrounds and job functions, with a demonstrated a track record of collaborating with diverse stakeholders, including other clinical, translational, computational, and life scientists
Strong interpersonal skills that motivate others to excel and achieve their very best
Passion for providing better medicine to patients in need
Preferred
Metabolic disease experience is very nice to have
Exposure to AI/ML methods is very nice to have
Benefits
401(k) plan with employer matching for contributions
Excellent medical, dental, and vision coverage as well as mental health and well-being support
Open, flexible vacation policy
Paid parental leave of at least 16 weeks to support parents who give birth, and 10 weeks for a new parent (inclusive of birth, adoption, fostering, etc)
Quarterly budget for books and online courses for self-development
Support to attend professional conferences that are meaningful to your career growth and role's responsibilities
New hire stipend for home office setup
Monthly cell phone & internet stipend
Access to free onsite baristas and daily lunch for employees who are either onsite or hybrid
Access to a free commuter bus and ferry network that provides transport to and from our South San Francisco HQ from locations all around the Bay Area
Company
insitro
Insitro is a drug discovery and development startup that utilizes machine learning and biology to transform drug discovery.
201-500 employees
H1B Sponsorship
insitro has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (12)
2024 (12)
2023 (12)
2022 (7)
2021 (4)
2020 (8)
Funding
Current Stage
Growth StageTotal Funding
$643MKey Investors
CPP InvestmentsAndreessen Horowitz
2021-03-15Series C· $400M
2020-05-26Series B· $143M
2018-05-02Series A· $100M
Leadership Team
Daphne Koller
Founder and CEO
D
Divya Kanichar
Director
Recent News
2026-01-06
Company data provided by crunchbase