Natera · 14 hours ago
Sr. Director/Director, Software Engineering - Early Cancer Detection (ECD)
San Carlos, CA
Full-time
Onsite
Director/Executive
$193K/yr - $241K/yr
10+ years expNatera is at the forefront of personalized genetic testing, transforming the management of disease worldwide. They are seeking a seasoned and visionary Sr. Director/Director of Engineering to lead the software strategy and development for their Early Cancer Detection (ECD) portfolio, focusing on building technical foundations for life-saving software products.
BiotechnologyGeneticsHealth DiagnosticsMedicalWomen's
Responsibilities
Define and execute the multi-year engineering roadmap for the ECD business unit, balancing the need for rapid prototyping with long-term commercial stability
Serve as the technical visionary for the ECD software suite, translating complex scientific and clinical requirements into robust, scalable software solutions
Champion a culture of "high agency" and urgency, driving the team to navigate ambiguity and deliver critical milestones in a fast-paced environment
Lead the end-to-end "Zero-to-One" development of ECD software solutions, from sample ordering to reports back to clinicians
Passion for building software that solves real problems for users & customers
Oversee the transition of research prototypes (e.g., CRC screening, MCED) into robust, commercial-grade software products
Drive cross-functional execution with Product Management, R&D, and Lab Operations to ensure software solutions meet user needs and business goals
Collaborate closely with Computational Biology and Bioinformatics teams to productionize complex algorithms into scalable clinical workflows
Proficiency with modern software development practices, including Agile/Scrum, CI/CD, and test-driven development
Ability to translate complex technical concepts for diverse stakeholders, including biologists, clinicians, and executives
Partner with Quality and Regulatory teams to ensure all software complies with FDA (PMA/510k), IEC 62304, and ISO 13485 standards
Serve as the engineering technical lead for regulatory submissions and audits, ensuring documentation and processes meet the highest standards of SaMD compliance
Embed compliance and security into the software development lifecycle (SDLC) without compromising development velocity
Recruit, mentor, and retain a world-class team of Full-Stack, DevOps, and Data Engineers
Foster an engineering culture of accountability, user-centered design, and continuous improvement
Provide technical mentorship and career development coaching to engineering managers and technical leads
Qualification
Required
10+ years of software engineering experience, with at least 5 years in a senior leadership role (Director or above) within the HealthTech, MedTech, or Biotech space
Proven track record of building 'Zero-to-One' products, taking complex software from initial concept through clinical validation to commercial launch
Deep experience in a highly regulated environment, with specific expertise in SaMD, FDA design controls, and HIPAA/GDPR compliance
Strong technical background in cloud-native architectures (AWS), distributed systems, and handling large-scale genomic or clinical datasets
BS/MS in Computer Science, Engineering, or a related field (PhD is a plus)
Benefits
Annual performance incentive bonus
Long-term equity awards
Comprehensive health benefits (medical, dental, vision)
401(k) with company match
Generous paid time off and company holidays
Additional wellness and work-life benefits
Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents
Free testing in addition to fertility care benefits
Pregnancy and baby bonding leave
Commuter benefits
Generous employee referral program
Company
Natera
Natera specializes in cell-free DNA testing to provide a more targeted interventions to oncology, women's health, and organ health.
5001-10000 employees
H1B Sponsorship
Natera has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (90)
2024 (72)
2023 (37)
2022 (71)
2021 (64)
2020 (40)
Funding
Current Stage
Public CompanyTotal Funding
$1.16BKey Investors
Sofinnova InvestmentsLightspeed Venture PartnersSequoia Capital
2023-09-07Post Ipo Equity· $250M
2022-11-15Post Ipo Equity· $400.05M
2022-03-16Post Ipo Equity· $5M
Leadership Team
Steve Chapman
CEO
Jonathan Sheena
Co-Founder, Board Member
Recent News
2026-01-08
Company data provided by crunchbase