Revolution Medicines · 1 day ago
Clinical Trial Manager
Redwood City, California, United States
Full-time
Hybrid
Mid, Senior Level
$120K/yr - $150K/yr
5+ years expRevolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. The Clinical Trial Manager will oversee clinical operations and manage clinical studies to ensure compliance with regulations and timely completion of trials.
Health CareLife ScienceMedical
Responsibilities
Clinical operations functional activities related to the execution of assigned clinical trials based upon department and corporate goals and objectives
Management of clinical studies and vendors to ensure studies are completed on time, within budget and in compliance with Standard Operating Procedures (SOPs), FDA regulations and International Council for Harmonization (ICH)/ GCP guidelines
Identify, engage, and manage the activities of clinical CROs and other clinical study providers (e.g., core labs, Electronic Data Capture (EDC) provider, and independent contractors) to execute clinical trials
Reviewing and contributing to the development of study-specific documentation including clinical trial protocols, case report forms, study guides/manuals, informed consent forms and clinical database
Reviewing monitoring reports and other study documentation as required
Oversight of the collection and management of clinical trial documentation to be filed in the Trial Master File (TMF)
Participation in team meetings and collaboration with other functional groups within the company (e.g., Clinical Development, Pharmacokinetics, Quantitative Sciences, Regulatory, QA, Finance, Legal, etc.) to achieve clinical study goals
Following up on assigned team action items and identification, escalation, and resolution of issues as needed
Collaboration with contracts specialist to review and negotiate Clinical Trial Agreements and site specific study budgets
Assessment of adequacy/feasibility of potential clinical investigators and sites including evaluating facilities, personnel, patient referral base, and adherence to GCP
Development of clinical study monitoring priorities and Monitoring Plan in conjunction with CRO
Conduct site visits (e.g., training visits, site initiation visits, monitoring visits), as required
Managing investigational product accountability and reconciliation process
Assistance with the preparation of safety, interim and final clinical study reports, and resolution of data discrepancies
Providing clinical trial support, mentoring, leadership, guidance, and direction to Clinical Research Associates (CRAs) assigned to clinical studies
Preparation and tracking of study participant enrollment projections vs. actuals and study budgets
Serving as primary clinical operations contact for internal and external (clinical sites, vendors, etc.) teams for assigned studies
Qualification
Required
BS or MS degree with a minimum of 5 years clinical operations experience in the pharmaceutical or biotech industry, preferably the majority in oncology drug development
Direct experience of running early-stage clinical trials within an industry environment
Strong working knowledge of FDA Regulations, ICH Guidelines and GCPs governing the conduct of clinical trials
Experience in selection of CROs/ vendors and management of external resources
A demonstrable record of strong vendor management and teamwork
Direct experience of managing clinical CROs
Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high-energy environment
Excellent written and verbal communication skills
Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important
Ability to travel (~25%)
Preferred
Experience in working with cooperative group studies and investigator sponsored trials, preferred
Experience of Global clinical trial operations outside the USA
Exceptional knowledge of the APAC region
Benefits
Competitive cash compensation
Robust equity awards
Strong benefits
Significant learning and development opportunities
Company
Revolution Medicines
Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.
501-1000 employees
H1B Sponsorship
Revolution Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (13)
2024 (18)
2023 (15)
2022 (8)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$2.25BKey Investors
Royalty PharmaBoxer CapitalNextech Invest
2025-06-24Post Ipo Debt· $250M
2024-12-02Post Ipo Equity· $750M
2023-03-02Post Ipo Equity· $323.6M
Leadership Team
Luan Wilfong
Chief Human Resources Officer
Steve Kelsey
President
Recent News
2026-01-11
The Motley Fool
2026-01-11
Company data provided by crunchbase