AstraZeneca · 1 week ago
Scientist - Conjugation and Purification
Gaithersburg, MD
Full-time
Onsite
Mid Level
$87K/yr - $131K/yr
3+ years expAstraZeneca is embarking on an exciting new frontier in medical science with its Aging Research Group, aiming to develop innovative therapeutics to extend human health span. The Scientist - Conjugation and Purification will be responsible for innovating and generating antibody drug conjugates, collaborating with diverse scientists, and maintaining laboratory operations.
BiopharmaBiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
Responsibilities
Conjugation, purification and characterization of precursors for radio-conjugates (RC) and ADC using multiple validated methodologies
Development and optimization of novel conjugation methodologies to improve RC and ADC properties
Radiolabeling of RC for in vitro and biodistribution evaluations
Collaborate and work with a diverse group of scientists across multiple therapeutic areas, chemistry, and process development to ensure timely progress in research projects and drive technological innovations
Partner with colleagues on laboratory maintenance, including maintenance of equipment and lab safety
Qualification
Required
Bachelor's or Master's degree in biotechnology, Pharmaceuticals Sciences, Chemical Biology, Biochemistry, Chemistry, or other relevant scientific field with 3+ years (BS degree) or 0-1 years (MS degree) of relevant experience
Hands-on experience and knowledge of protein purification using HIC, IEX, SEC and affinity chromatography. Experience with GE AKTA FPLC preferred
Working knowledge of characterization using analytical techniques like Hydrophobic Interaction Chromatography (HIC)-HPLC, Size Exclusion Chromatography (SEC), Liquid chromatography–mass spectrometry (LC-MS), Ion-Exchange (IEX), Reversed Phase (RP)-HPLC, etc
Proven ability to work independently, effectively plan and organize work activities and prioritize task completion to meet project deadlines
Demonstrated experience in optimizing/troubleshooting protocols with a problem-solving mindset and maintains a detailed laboratory notebook
Preferred
Demonstrated hands-on experience in the generation of RC and ADC
Experience with radiochemistry and related assays
Excellent written and verbal communication skills and effective presentation of complex scientific data to cross-functional and senior management
Benefits
Qualified retirement programs
Paid time off (i.e., vacation, holiday, and leaves)
Health, dental, and vision coverage in accordance with the terms of the applicable plans
Short-term incentive bonuses
Equity-based awards for salaried roles
Commission payment eligibility (sales roles)
401(k) plan
Company
AstraZeneca
AstraZeneca is a pharmaceutical company that discovers, develops, manufactures, and markets prescription medicines. It is a sub-organization of Investor.
10001+ employees
H1B Sponsorship
AstraZeneca has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2021 (2)
2020 (11)
Funding
Current Stage
Public CompanyTotal Funding
$5.26B2024-07-30Post Ipo Debt· $1.51B
2023-02-28Post Ipo Debt· $2.25B
2023-02-24Post Ipo Debt· $1.5B
Leadership Team
Pascal Soriot
Chief Executive Officer
Aradhana Sarin
Group CFO and Executive Director
Recent News
2026-01-21
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2026-01-20
2026-01-20
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