AbbVie · 1 day ago
Principal Research Scientist I, Lipid Design and Formulations Development
San Diego, CA
Full-time
Onsite
Senior Level, Lead/Staff
$121K/yr - $230K/yr
6+ years expAbbVie is dedicated to discovering and delivering innovative medicines to address serious health issues. They are seeking a highly motivated Formulation Scientist to lead projects in lipid design and formulation development, focusing on targeted LNP drug products.
BiotechnologyFinancial ServicesHealth CareMedicalPharmaceuticalVenture Capital
Responsibilities
Independently lead research efforts through deep technical understanding and work collaboratively within a cross-functional product development team to drive design, functional screening, development and production of novel tLNP formulations for targeted, extra hepatic delivery of nucleic acid payloads
Discover and optimize novel lipid designs and applications from diverse structural families for LNP platform technology development
Collaborate with various groups across the organization including mRNA, analytical, conjugation, antibody and CMC process development groups to advance pipeline programs
Routinely act as a group leader on formulation projects and provide mentorship to a small group of research associates
Contribute to formulations/process development sections of regulatory filings (IND, NDA etc.)
Review scientific literature, patents, scientific abstracts to stay up to date on latest in the field. Provide scientific expertise in the organization with special emphasis on lipid nanoparticle-based drug targeting delivery systems for nucleic acids
Qualification
Required
BS or equivalent education and extensive, typically 14+ years of industry experience; MS or equivalent education with typically 12+ years of industry experience; PhD with typically 6+ years of industry experience in scientific area of discipline
Deep technical prowess is required with respect to lipid chemistry and LNP formulation. Demonstrated ability to establish new capabilities and innovate strategies in pursuit of scientific excellence
Must possess in depth understanding of all aspects of formulation development as well as downstream characterization including physicochemical, stability and biological evaluation
Experience with process: lipid nanoparticle formulation and purification processes, and/or experience with process development, scale-up/out, engineering and GMP manufacturing of biologic drug product processes are highly desired
Must be an independent thinker with a passion for developing novel formulation technologies
Details oriented with good organization skills, great troubleshooting skills, team player, excellent oral and written communication skills are necessary for this position
Preferred
PhD in Chemistry, Biochemistry, Bioengineering, or Pharmaceutical Sciences with experience in the design and development of nanoparticle-based drug delivery systems or complex biologics
Experience with supervision, mentorship, or training of other team members
Good track record of scientific publications and patents in the field of lipid nanoparticle-based drug delivery systems is desired
Experience in contributing to formulation and pharmaceutical development sections of regulatory filings is highly desirable
Benefits
Paid time off (vacation, holidays, sick)
Medical/dental/vision insurance
401(k)
Company
AbbVie
AbbVie is a biopharmaceutical company focused on immunology, oncology, neuroscience, virology, and aesthetics. It is a sub-organization of AbbVie.
10001+ employees
H1B Sponsorship
AbbVie has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (273)
2024 (190)
2023 (225)
2022 (284)
2021 (186)
2020 (186)
Funding
Current Stage
Public CompanyTotal Funding
$15B2024-02-27Post Ipo Debt· $15B
2023-03-08Post Ipo Equity· $0.25M
2012-12-20IPO
Leadership Team
Robert Michael
Chairman of the Board and Chief Executive Officer
Micah Bregman
Vice President, Global Strategy and Pipeline, Allergan Aesthetics
Recent News
2026-01-09
2026-01-09
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