Senior Computational Biologist jobs in United States
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Pfizer · 11 hours ago

Senior Computational Biologist

Pfizer’s Machine Learning and Computational Sciences group is seeking a highly skilled computational biologist with experience in bioinformatics workflow and data management method development. The role involves analyzing high-throughput sequencing and multi-omics data to support the development of analytical assays and the characterization of oligonucleotide-based therapeutics.

BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
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Responsibilities

Develop computational methods and workflows to support Pfizer’s portfolio projects focused on nucleic acid products and medicines
Streamline and automate complex analytical tasks for short-read and long-read sequencing data to improve efficiency and maintain reproducibility
Provide support for data analysis, visualization, interpretation of results, and experimental design feedback across multiple projects
Conduct detailed bioinformatics and statistical analyses and maintain documentations within a regulated system
Work closely with Research & Development scientists to generate new scientific insights
Manage and maintain computational infrastructure and database systems

Qualification

Computational BiologyBioinformaticsPythonBiostatisticsNextflowHigh-throughput SequencingData ManagementInterpersonal SkillsPresentation SkillsAttention to Detail

Required

Ph.D. degree in computational biology, biostatistics, computer science, or a related technical field with 0-5 years of industrial experience in the analysis of high-throughput sequencing and other omics datasets
Demonstrated high proficiency in programming, with strong skills in Python and workflow languages to efficiently execute and automate workflows and data management tasks
Experience in computational tool and package development including version control, unit testing, deployment, and documentation
A strong interest in continuously learning and engaging with emerging biological initiatives
Attention to detail, documentation skills, ability to multitask, and effective interpersonal and presentation skills

Preferred

Extensive experience in developing high-throughput sequencing pipelines using the Nextflow workflow development language on a cloud-based platform
An in-depth understanding of the statistical methods commonly used in omics analyses
Familiarity with cGMP regulatory requirements for data and infrastructure security controls
Experience analyzing nucleic acid molecules, large molecules, and vaccines
A strong record of well-cited journal publications and presentations

Benefits

401(k) plan with Pfizer Matching Contributions
Pfizer Retirement Savings Contribution
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage

Company

Pfizer is a biopharmaceutical company that discovers, develops, and delivers medicines and vaccines.

Funding

Current Stage
Public Company
Total Funding
$38B
Key Investors
Starboard Value
2025-11-21Post Ipo Debt· $6B
2024-10-07Post Ipo Equity· $1B
2023-05-16Post Ipo Debt· $31B

Leadership Team

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Albert Bourla
Chief Executive Officer
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Ian Read
Chief Executive Officer
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Company data provided by crunchbase