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Lawrence Livermore National Laboratory · 1 day ago

Molecular & Cellular Biology - Staff Scientist

Livermore, CA

Full-time

Onsite

Lead/Staff

$83K/yr - $154K/yr

Lawrence Livermore National Laboratory (LLNL) is focused on strengthening the United States’ security through innovative scientific solutions. The Staff Scientist will engage in the development of therapeutics and vaccines against infectious diseases, contributing to a multidisciplinary team and performing a variety of molecular biology techniques.

Information TechnologyMarket ResearchSecurity

Growth Opportunities

No H1B

Security Clearance Required

U.S. Citizen Only

Responsibilities

Operate and support automated and high-throughput workflows, including plate-based assay systems

Maintain mammalian cell lines and cell culture equipment for assay development

Express and purify proteins to generate reagents for functional, biochemical, and immunological studies

Perform standard molecular biology techniques (e.g., DNA preparation, DNA/protein quantification, SDS-PAGE)

Assist in the development and optimization of immunoassays and affinity assessment methods, including BLI, ELISA, and fluorescence-based platforms

Evaluate datasets generated from high-throughput assays and troubleshoot experimental workflows as needed

Contribute to the maintenance of a BSL-2 laboratory, including ordering, equipment upkeep, inventory control, and ES&H safety guideline implementation

Maintain accurate and detailed laboratory notebooks and communicate results with relevant team members

Perform other duties as assigned

Develop and optimize immunoassays and affinity assessment methods, including SPR, BLI, ELISA, and fluorescence-based platforms (e.g., MSD, Gyrolab, AlphaLISA)

Provide solutions to problems of limited complexity that require creative use of established and/or innovative methods

Analyze existing workflow procedures in comparison to the literature and provide suggestions to improve efficiency, robustness, and overall performance

Provide occasional training on laboratory procedures to other employees or contribute to cross-functional teams

Qualification

Molecular BiologyProtein PurificationAssay DevelopmentCell CultureImmunoassaysBiochemical StudiesStatistical SoftwareMicrosoft OfficeTeam CollaborationProblem-SolvingCommunication Skills

Required

Ability to secure and maintain a U.S. DOE Q-level security clearance which requires U.S. citizenship

BS degree in Molecular Biology, Biochemistry, or related field, or the equivalent combination of education and related experience

Fundamental knowledge of sterile techniques, culturing and maintenance of microbiological and tissue cultures, and media preparation

Fundamental knowledge of molecular biology techniques (e.g., ELISA, microscopy, protein purification, SDS PAGE, BLI)

Familiarity with common Microsoft Office applications and other scientific software

Ability to learn and apply new concepts with guidance; performs tasks accurately within a general and stable environment, following established guidelines and procedures

Works effectively in a fast-paced, multidisciplinary environment both independently and as a team with a diverse set of scientists, and other technical and administrative staff

Foundational problem-solving skills to implement solutions of limited complexity

Sufficient verbal and written communication skills to collaborate effectively in a team environment and present and explain technical information