Pathos · 20 hours ago
Research Associate II
New York City, NY
Full-time
Onsite
Mid Level
3+ years expPathos is a next-generation biotech company focused on revolutionizing drug development through AI. They are seeking a highly motivated Research Associate II to develop and execute ex-vivo assays that support their oncology clinical pipeline, with a focus on understanding drug mechanisms and validating biomarkers.
Artificial Intelligence (AI)BiotechnologyLife ScienceMedicalTherapeutics
Responsibilities
Design and executing medium-to-high-throughput drug screen assays for testing tumor kill and pharmacodynamic effects using Incucyte
Characterization of assay samples for proteomics, RNA, DNA and epigenetic changes that explain molecular mechanisms of resistance and tolerability
Collaboration with a world-class computational team to interpret multi-omic data to improve AI predictions and drive biomarker strategy for clinical trials
Building and maintaining a biobank of primary tumor tissues and cell lines for translational experiments
Perform routine and advanced cellular and molecular biology techniques, including primary tumor sample processing, cell culture, transfection, nucleic acid extraction, PCR/qPCR, Western blotting, and immunostaining
Inventory management, vendor coordination, equipment maintenance scheduling, and compliance with safety protocols
Sample tracking, experiment recording and data management using LIMS system (Benchling)
Contribution of biological insights to the preparation of reports, presentations, and publications for clinical trials and FDA documents
Qualification
Required
B.S. or M.S. in Biology, Molecular Biology, Genomics, or a related field
3–5 years of hands-on experience in an oncology research or industry laboratory setting
Strong expertise in cell culture techniques, including the maintenance of human cancer cell lines, dissociation and expansion of primary solid tumor tissues from surgical resection
Competency in setting up drug functional assays for small molecules and antibody therapeutics required
Familiarity with flow cytometry and/or immunohistochemistry in FFPE is highly desirable
Proficiency in genomic assays (e.g. RNAseq, DNAseq and ChIP) and CRISPR technology is also preferred
Preferred
Experience with 3D culture systems such as Matrigel
Company
Pathos
Pathos is a biotechnology company that leverages AI to accelerate oncology drug development.
11-50 employees
H1B Sponsorship
Pathos has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2023 (1)
Funding
Current Stage
Late StageTotal Funding
$447MKey Investors
New Enterprise Associates
2025-05-15Series D· $365M
2024-10-29Series C· $62M
2023-03-02Series Unknown· $20M
Leadership Team
Ryan Fukushima
Co-Founder
Recent News
2025-10-27
2025-09-19
Company data provided by crunchbase