Broad Institute of MIT and Harvard · 1 day ago
Research Associate II: AAV production, purification, and analytical analysis
Cambridge, MA
Full-time
Onsite
Entry, Mid Level
$58K/yr - $81K/yr
2+ years expBroad Institute of MIT & Harvard is dedicated to transforming medicine by accelerating the understanding and treatment of disease. They are seeking a Research Associate II to produce and purify adeno-associated viral vectors and perform analytical testing to assess their purity and potency, contributing to gene therapy projects.
BiotechnologyClinical TrialsLife Science
Responsibilities
Maintain adherent and suspension cell lines and perform transfections for AAV production
Perform affinity chromatography and ultracentrifugation for AAV purification
Quantify AAV titers and particles and run quality control assays
Perform basic molecular biology experiments such as plasmid construction, sequencing and QC assays, quantitative PCR, and digital droplet PCR
RNA, DNA and protein extractions from cell or tissue samples
Run reporter assays and/or flow cytometry
Maintain meticulous records using an electronic laboratory notebook and document, compile, and analyze experimental data
Assist with laboratory organization, ordering, and the operation and maintenance of laboratory equipment, and perform other duties as assigned
Attend and contribute to team meetings
Contribute to scientific manuscripts and conference presentations
Qualification
Required
Ability to work flexibly to support multiple projects
B.A. or B.S. in Biology or related field with 2+ years of relevant experience, or an M.S. in a related field with 0+ years of experience
Hands-on experience with mammalian cell culture, transfections, and sterile technique
Experience working in a BL2 or BL2+ environment
Exceptional organizational and time management skills, electronic lab notebook practices and careful attention to detail
Outstanding interpersonal and communication skills and attention to detail
Strong work ethic, reliability, and desire to work in a team
Benefits
Medical
Dental
Vision
Life
Disability insurance
A 401(k) retirement plan
Flexible spending and health savings accounts
At least 13 paid holidays
Winter closure
Paid time off
Parental and family care leave
An employee assistance program
Among other Broad benefits
Company
Broad Institute of MIT and Harvard
The Broad Institute brings together a diverse group of individuals from across its partner institutions — undergraduate and graduate students, postdoctoral fellows, professional scientists, administrative professionals, and academic faculty.
1001-5000 employees
H1B Sponsorship
Broad Institute of MIT and Harvard has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (108)
2024 (59)
2023 (73)
2022 (68)
2021 (70)
2020 (93)
Funding
Current Stage
Late StageTotal Funding
$283.25MKey Investors
MacArthur FoundationAlzheimer's Foundation of AmericaMassachusetts Life Sciences Center
2025-11-18Grant· $100M
2020-08-11Grant
2019-09-09Grant· $0.75M
Leadership Team
Dan Shore
Chief Financial Officer
Anne Carpenter
Institute Scientist and Imaging Platform Senior Director
Recent News
2025-12-02
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2025-11-20
Medical Xpress - latest medical and health news stories
2025-11-19
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