Pharmaron · 1 week ago
Senior Scientist / Associate Principal Scientist, Chemical Engineering R&D
Coventry, RI
Full-time
Onsite
Senior Level, Lead/Staff
$100K/yr - $1,600K/yr
5+ years expPharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. They are seeking a Senior Scientist / Associate Principal Scientist in Chemical Engineering R&D to perform hands-on small-molecule process development and scale-up from laboratory to commercial manufacturing, utilizing chemistry, engineering, and data analysis to optimize manufacturing processes.
BiotechnologyChemicalPharmaceutical
Responsibilities
Perform hands-on small molecule process development and scale-up work
Use Design of Experiments (DoE) for process screening, optimization, and robustness studies
Define CPPs, PARs, NORs, and contribute to the development of scalable control strategies
Apply process analytical technology (PAT) and process modeling
Evaluate and model kinetics, mixing, mass/heat transfer, and reactor performance
Conduct independent research to achieve mechanistic understanding for rational process design
Design and optimize key unit operations including crystallization, filtration, drying, distillation, and extraction
Use process modeling tools to inform scale-up strategies
Translate lab-scale findings into actionable parameters for kilo lab and GMP manufacturing
Drive cycle time reduction and process intensification initiatives
Implement innovative technologies such as continuous flow chemistry and automation platforms
Support internal and external tech transfer activities, including scale-up studies, modeling, and verification experiments
Support development of complex transformations such as catalytic hydrogenation
Exhibit a mindset of safety and quality compliance
Collaborate cross-functionally within US, UK, and China-based teams
Qualification
Required
Education Minimum Requirement: The position requires either a BS and/or MS in Chemical Engineering (or comparable) from an accredited college/university plus at least 5 years of relevant work experience in small-molecule chemical process development - OR - a PhD in Chemical Engineering (or comparable) from an accredited college/university with at least 2 years of relevant work experience post PhD defense
Experience performing lab-based research/process development in a chemical engineering-related area
Experience with organic chemical synthesis and wet chemistry
Experience with small molecule pharmaceutical drug substance development
Experience applying statistical experimental design (i.e. Design of Experiments) and/or process modeling
A high level of innovation, creativity, and self-initiative
Highly effective communication and collaboration skills
Good organizational, interpersonal, writing, and time management skills
Preferred
Experience with process scale-up and/or technology transfer, moving from laboratory to pilot plant or production scale
Familiarity with concepts and application of cGMP and GDP during pharmaceutical development and production
Demonstrated experience with chemical engineering-related technology development
Familiarity with kilo-scale laboratory equipment
Experience with process modeling (e.g., population balance modeling, distillation modeling)
Knowledge with milling equipment (spiral jet mills, pin mills, co-mills, rotor-stator wet mills)
Benefits
Insurance including Medical, Dental & Vision with significant employer contributions
Employer-funded Health Reimbursement Account
Healthcare & Dependent Care Flexible Spending Accounts
100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance
401k plan with generous employer match
Access to an Employee Assistance Program
Company
Pharmaron
Pharmaron is a contract research organization that offers research and development services for the life science industries.
10001+ employees
Funding
Current Stage
Public CompanyTotal Funding
$907.82MKey Investors
GL Capital
2019-11-22Post Ipo Equity· $587.82M
2019-01-28IPO
2015-12-14Series Unknown· $280M
Leadership Team
Katherine Lee
Chief Business Officer
Recent News
Precedence Research
2025-11-07
Business Wire
2025-10-29
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