CHEManager International · 11 hours ago
Tissue Autoradiography Scientist
Madison, WI
Full-time
Onsite
Mid, Senior Level
2+ years expCHEManager International is seeking a Tissue Autoradiography Scientist to join the Nirschl and Kolb laboratories at the University of Wisconsin-Madison. The successful candidate will lead the discovery and development of novel PET imaging tracers targeting pathological protein aggregates in neurodegenerative diseases and will be responsible for executing custom tissue-based assays.
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No H1B
Responsibilities
Conducts literature reviews, prepares reports and materials, and disseminates information to appropriate entities
Serves as a main point of contact and liaison with internal and external stakeholders providing information and representing the interests of a specialized research area
Assists with the identification of research problems and the development of research methodologies and procedures
Attends and assists with the facilitation of scholarly events and presentations in support of continued professional development and the dissemination of research information
Assists with ordering, tracking, and maintenance of lab instruments and radiolabeled compounds; ensuring appropriate safety, documentation and regulatory compliance (e.g., EH&S, ORS)
Collects and analyzes research data, conducts experiments and interviews, and documents results according to established policies and procedures under general supervision and limited responsibility
Contributes to invention disclosures and intellectual property documentation related to new imaging agents
Writes or assists in developing grant applications and proposals to secure research funding
Qualification
Required
A minimum of 2 years of post-doctoral experience or equivalent industry experience
PhD Degree required; focus in bioanalytical science, biochemistry, molecular biology or a related field required
Preferred
Advanced experience in tissue-based assay development, including autoradiography and radioligand binding assays using both tissue slices and purified proteins
Proficiency in biochemical extraction and purification of pathological proteins (e.g., α-synuclein, tau) from human and animal brain tissue
Demonstrated ability to perform competitive binding and displacement assays to quantify tracer specificity and affinity
Experience conducting Surface Plasmon Resonance (SPR) experiments or related biophysical assays for assessing molecular interactions
Familiarity with histopathological techniques, including immunostaining and tissue sectioning for quantitative analysis
Strong record of collaborative research in interdisciplinary, multi-site translational programs
Ability to independently troubleshoot complex experimental systems and contribute to project design
Commitment to maintaining high standards of scientific rigor, data documentation, and reproducibility
Excellent communication skills and the ability to work effectively in a collegial academic research environment
Benefits
Generous vacation, holidays, and sick leave
Competitive insurances and savings accounts
Retirement benefits
Company
CHEManager International
Wiley’s leading media brand providing first-hand information on the global chemical, life science and process industries
201-500 employees
Funding
Current Stage
Growth StageCompany data provided by crunchbase