Mount Sinai Morningside · 1 month ago
Postdoctoral Fellow-MSH-30025-245
New York, NY
Full-time
Onsite
Mid, Senior Level
$72K/yr - $80K/yrMount Sinai Morningside is a prominent academic medical institution seeking a Postdoctoral Fellow to join the Wagenblast Lab. The fellow will investigate the role of TET2-mutant clonal hematopoiesis in cancer progression, focusing on the remodeling of the bone marrow and the evaluation of therapeutic strategies.
Hospital & Health Care
Responsibilities
Generate genome-edited hematopoietic stem/progenitor cells (HSPCs) using CRISPR/Cas9
Perform xenotransplantation of human HSPCs into immunodeficient mice
Analyze bone marrow and tumor samples via flow cytometry, immunohistochemistry, and histology
Conduct bioluminescence imaging to monitor metastasis progression
Assist in spatial transcriptomics using 10x Visium HD and single-cell RNA sequencing workflows
Maintain primary cell cultures, perform viral transduction, and cytokine assays
Participate in manuscript preparation and presentation of findings
Qualification
Required
PhD in cancer biology, hematology, immunology, or a related biomedical discipline
Demonstrated experience in molecular biology and murine models
Strong communication skills and ability to work independently and collaboratively in a team
Prior experience with CRISPR-based genome editing and/or xenograft models
Preferred
Familiarity with hematopoietic stem cell biology and immune phenotyping preferred
Experience analyzing high-dimensional datasets (e.g., scRNA-seq) is an asset but not required
Company
Mount Sinai Morningside
At Mount Sinai Morningside, we offer exceptional clinical care and research within the comfort of a neighborhood hospital known for compassion and sensitivity.
Founded in 1846
1001-5000 employees
H1B Sponsorship
Mount Sinai Morningside has a track record of offering H1B sponsorships. Please note that this does not
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2025 (5)
2024 (3)
2023 (26)
2022 (20)
2021 (6)
2020 (20)
Funding
Current Stage
Late StageLeadership Team
Faye Reiff-Pasarew
Deputy CMO, Associate Chief of Hospital Medicine, Assistant Professor of Internal Medicine
Lucy Xenophon, MD, MPH
Chief Transformation Officer
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