Cogent Biosciences · 6 days ago
Executive Medical Director
United States
Full-time
Remote
Director/Executive
$360K/yr - $410K/yrCogent Biosciences is a publicly traded biotechnology company dedicated to developing precision therapies for genetically defined diseases. The Executive Medical Director will play a key role in designing rational precision therapies and provide strategic medical leadership for the company's research pipeline of precision small molecules.
BiotechnologyHealth CareMedicalTherapeutics
Responsibilities
Work closely with Cogent’s clinical development and research teams to oversee early clinical development activities and provide strategic and medical leadership to support the growing research pipeline and early-stage assets at Cogent
Contribute to and partner on the development of strategic initiatives and various organizational initiatives in Clinical Development
Help develop a more structured decision-making process for which programs advance into phase 1 and subsequently beyond clinical proof of concept
Participate in the strategic prioritization of programs in the pipeline
Play an active role in the technical and leadership development of Clinical Development team members via management of Medical Director(s) and mentoring of team members
Contribute to the growth of the early development organization at Cogent through development of strategies, templates, and processes to advance early-stage assets
Participate in due diligence activities and partnership discussions when appropriate
Provide medical, disease-specific, and development perspective for specific research programs or broader research initiatives as required
Provide medical expertise to assess the clinical relevance and therapeutic potential of early-stage drug candidates, considering their mechanism of action and potential patient populations
Foster strong collaborative relationships with research teams to facilitate the translation of scientific discoveries into clinical development strategies
Review and lead the interpretation of clinical trial data and collaborate on the preparation of clinical study reports, presentations, and publications for scientific conferences and peer-reviewed journals
Oversee the writing of all critical program documents including but not limited to study protocols, the investigators’ brochure, regulatory filings and submissions, abstracts, manuscripts and publications, clinical study reports, etc
Collaborate with the regulatory team to develop briefing documents and other regulatory documents in support of IND submissions
Provide medical input into all other documents in support of the clinical development plan
Provide oversight of early development clinical programs ensuring execution and completion of clinical trials in alignment with regulations, ICH/GCP guidelines, and internal SOPs
Provide and/or oversee primary medical monitor responsibilities, including oversight of trial subject safety and clinical data review and interpretation
Foster a collaborative and high-performing team environment
Represent the company at scientific and regulatory meetings, conferences, and advisory boards
Work with external partners, including CROs, academic institutions, and key opinion leaders (KOLs), to ensure successful execution of clinical trials and delivery of the integrated clinical development strategy
Develop a deep understanding of the clinical and competitive landscape and work with the asset team to develop the target product profile
Qualification
Required
MD required, with experience in hematology / medical oncology strongly preferred
Significant experience in clinical development at a biotechnology or pharmaceutical company; experience at a small biotech company preferred
Significant knowledge and experience in the design and execution of early phase clinical trials with experience in overseeing global clinical trials from design through execution
Demonstrated experience in clinical research, including creating clinical development plans, and designing, planning and monitoring clinical trials, particularly Phase 1 first-in-human and proof-of-concept
In-depth knowledge of regulatory requirements and compliance in clinical trials
Experience with preparing clinical sections of regulatory submissions (e.g., INDs)
Experience working in a matrix team and in direct line management
Strong understanding of targeted therapies, genetic biomarkers, and genetically defined diseases, particularly in the context of oncology
A working knowledge of biostatistics, translational sciences, clinical pharmacology, scientific and other technical disciplines and processes intimate with the drug development process
Outstanding communication skills (written and verbal, both formal and informal)
Ability to manage multiple projects and initiatives simultaneously in a fast-paced environment
Effective skills directed toward driving collaboration, achieving results, influencing, and resolving conflicts across internal and external project teams
Benefits
Competitive pay
Performance-based bonus
Stock options
Insurance coverage (health, dental, life, and disability)
Competitive time-off
A 401(k) plan
Commuter/parking benefits
Company
Cogent Biosciences
Cogent Biosciences is a biotechnology company that develops therapies for solid cancer tumors.
Founded in 2014
51-200 employees
H1B Sponsorship
Cogent Biosciences has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (1)
2023 (3)
Funding
Current Stage
Public CompanyTotal Funding
$1.6BKey Investors
Commodore CapitalFairmount Funds ManagementSquare 1 Bank
2025-11-10Post Ipo Equity· $200M
2025-11-10Post Ipo Debt· $200M
2025-07-08Post Ipo Equity· $230M
Leadership Team
Andrew Robbins
CEO and President
A
Abb Hayden
Senior Vice President of Sales
Recent News
2025-12-31
Company data provided by crunchbase