Mount Sinai Morningside · 3 months ago
Postdoctoral Fellow-MSH-32050-003
Mount Sinai Morningside is a prominent academic medical system committed to excellence in patient care and innovation. The Postdoctoral Fellow will lead research projects involving the differentiation of human pluripotent stem cells into neurons and astrocytes, oversee junior lab members, and manage experimental timelines and data integrity.
Hospital & Health Care
Responsibilities
Leading the differentiation of hPSCs into cortical neurons and astrocytes
Generating and maintaining 3D midbrain organoids for disease modeling and functional assays
Designing and executing assays to evaluate lysosomal activity, polyamine distribution, and α-synuclein accumulation (e.g., DQ-BSA assay, LAMP1 staining, ICC)
Performing confocal imaging, molecular biology (qPCR, Western blot), and image-based phenotyping
Supervising and mentoring junior lab members, including graduate students, research technicians, and interns
Managing experimental timelines, data integrity, and regulatory compliance
Developing and refining standard operating procedures (SOPs) for stem cell and organoid workflows
Leading experimental planning and data analysis using ImageJ, CellProfiler, Prism, and/or R
Preparing manuscripts, figures, and presentations for scientific publications and conferences
Collaborating with the principal investigator on grant proposals, experimental strategy, and lab-wide initiatives
Qualification
Required
A recent Ph.D. graduate with demonstrated experience in any of the following fields: cell biology, molecular biology, biochemistry, neuroscience, and developmental/stem cell biology, bioengineering
Experience in iPSC cell culture and differentiation
Experience in molecular and cell biology
Experience in CRISPR
Experience in bioengineering
Experience in confocal microscopy
Experience in calcium imaging and optogenetics
Experience in mouse models
Experience in computational biology
Experience in single cell/nuclei RNAseq
4-5 years of experience
Company
Mount Sinai Morningside
At Mount Sinai Morningside, we offer exceptional clinical care and research within the comfort of a neighborhood hospital known for compassion and sensitivity.
H1B Sponsorship
Mount Sinai Morningside has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (3)
2023 (26)
2022 (20)
2021 (6)
2020 (20)
Funding
Current Stage
Late StageLeadership Team
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