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Kyowa Kirin, Inc.- U.S. · 3 weeks ago

Associate Scientist I- Cell and Gene Therapy

La Jolla, CA

Full-time

Onsite

Senior Level, Lead/Staff

$120K/yr - $125K/yr

8+ years exp

Kyowa Kirin is a fast-growing global specialty pharmaceutical company that applies state-of-the-art biotechnologies to discover and deliver novel medicines. The Associate Scientist will support the cell therapy pipeline programs by enabling gene editing, evaluating new technologies, and contributing scientific knowledge to project teams.

Pharmaceuticals

H1B Sponsor Likely

Responsibilities

Support Cell and Gene Therapy pipeline projects by working with Project Leads to enable gene editing and generate new molecular workflows

Serve as a Project Lead for technology themed projects if needed

Identify, evaluate, and implement new gene editing technologies

Contribute scientific and technical knowledge to project and support teams

Design, initiate, and optimize molecular, cell based, and analytical methods to support the Research, Technical Operations, and In Vivo Pharmacology teams

Maintain compliance with regulatory guidelines and internal standards, and prepare necessary documentation for project reviews (proposals, monthly, quarterly, annual, or study reports), patent applications, publications, and/or animal, biosafety, or human subject protocols

Present research at project meetings and efficiently record experiments and data in laboratory notebooks, databases and monthly reports

Qualification

Gene editing technologiesCell culture methodologiesMolecular biologyCRISPRNext-generation sequencing (NGS)Molecular cloningCell engineering processesAntibody/protein engineeringMS Office SuiteProject managementTechnical documentationPresentation skillsTeam collaboration

Required

BS required

8 years of hands-on experience and in-depth knowledge of cell and gene therapy techniques and gene editing

Extensive experience in gene editing technologies, including CRISPR, base editing, prime editing, or transposase/recombinase-based editing

Strong background in molecular biology, with practical experience in NGS, molecular analytical development, gene editing design, and molecular cloning

Expertise in cell culture methodologies, development, and characterization of cell therapy products including HSCs, iPSCs, and/or CAR-T cells

Extensive experience in the molecular characterization of cell therapies, with a strong preference for expertise in NGS

Strong knowledge of industry standard gene editing techniques and analytics including CRISPR, guide RNA design and screens, indel analysis, knock-out and knock-in analysis, NGS, ddPCR

Solid understanding of cellular, molecular, and immunological techniques including cloning, ELISA, multi-color flow cytometry, in vitro functional assays, cell based assays, reporter assays

Experience in cell engineering processes including knowledge of cell line generation workflows and experience developing therapeutic engineered cells such as CAR-T

Expertise in cell culture techniques including culture of primary cells, iPSCs, HSCs, and cell lines from multiple species and cell manipulation techniques including transfection, nucleofection, and transduction

Experience with cell characterization including multicolor flow cytometry, FACS, MACS, and single cell isolation techniques

Proficient in MS Office Suite

Preferred

MA/MS preferred in a related scientific discipline

Familiarity with CAR design, engineering, screening, and assay development

Experience in developing high-throughput screening platforms for cells, proteins, or antibodies

Background in antibody/protein engineering, protein production, and purification

Experience in virus production, transduction, and analytics

Experience in antibody or protein production, purification, and analysis

Benefits

401K with company matching

Discretionary Profit Sharing

Annual Bonus Program (Sales Bonus for Sales Jobs)

Generous PTO and Holiday Schedule which includes a Summer and Winter Shut-Down, Sick Days and, Volunteer Days

Healthcare Benefits (Medical, Dental, Prescription Drugs and Vision)

HSA & FSA Programs

Well-Being and Work/Life Programs

Life & Disability Insurance

Concierge Service

Pet Insurance

Tuition Assistance

Employee Referral Awards

Company

Kyowa Kirin, Inc.- U.S.

Kyowa Kirin is a global specialty pharmaceutical company that applies state-of-the-art biotechnologies to discover and deliver novel medicines.

Founded in 1949

Princeton, New Jersey, US

501-1000 employees

https://kkna.kyowakirin.com/

H1B Sponsorship

Kyowa Kirin, Inc.- U.S. has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Represents job field similar to this job

Trends of Total Sponsorships

2025 (1)

2022 (1)

2021 (1)