Proclinical Staffing ยท 18 hours ago
Senior Research Scientist, Myeloid Disease
Wilmington, DE
Full-time
Onsite
Senior Level
5+ years expProclinical Staffing is working alongside a pharmaceutical company seeking to hire a Senior Research Scientist, Myeloid Disease, to join the team. This position will be responsible for performing in-vitro studies for cancer drug discovery programs and developing relevant pre-clinical model systems to identify and validate novel therapeutic targets.
Staffing & Recruiting
Hiring Manager
Michael Raletz
Responsibilities
Leverage chemical and genetic modalities to design, execute, and interpret experiments with a high degree of scientific independence and accountability
Establish and deploy disease-relevant preclinical models to interrogate target biology and address complex mechanistic hypotheses
Contribute to small- and large-molecule screening efforts across exploratory research and lead optimization programs, ensuring data quality and translational relevance
Collaborate with other functional groups within drug discovery to achieve shared goals
Flexibility to acquire additional competencies and skillsets as needed
Excellent verbal and written communication skills, specifically in conveying complex and technical information into a clear and understandable format to both internal and external audiences
Qualification
Required
Bachelor's degree in molecular biology, stem cell biology, or a related discipline with a minimum of five (5) years of relevant industry experience, or Master's in a related field with a minimum of (2) years of relevant industry experience, or a Ph.D. in a related field with at least three (3) years of postdoctoral or equivalent research experience
Demonstrated track record of developing, optimizing, and executing functional cellular assays to assess proliferation, differentiation, and apoptosis in biologically relevant model systems
Strong theoretical grounding combined with hands-on expertise in assays utilizing primary stem cells; experience in hematopoietic stem cell biology or myeloid malignancies (MPN, MDS or AML) is strongly preferred
Proven technical proficiency in core molecular and cellular biology methodologies, including ELISA, MSD-based assays, Western blotting, multicolor flow cytometry, and CRISPR/Cas9 gene-editing platforms; experience with CRISPR-based screening approaches is a plus
Experience leveraging advanced 3D tissue or organoid models, to recapitulate disease biology in physiologically relevant contexts
Leverage chemical and genetic modalities to design, execute, and interpret experiments with a high degree of scientific independence and accountability
Establish and deploy disease-relevant preclinical models to interrogate target biology and address complex mechanistic hypotheses
Contribute to small- and large-molecule screening efforts across exploratory research and lead optimization programs, ensuring data quality and translational relevance
Collaborate with other functional groups within drug discovery to achieve shared goals
Flexibility to acquire additional competencies and skillsets as needed
Excellent verbal and written communication skills, specifically in conveying complex and technical information into a clear and understandable format to both internal and external audiences
Preferred
Experience with oncogenic signaling pathways and targeted therapies is an advantage
Experience in hematopoietic stem cell biology or myeloid malignancies (MPN, MDS or AML) is strongly preferred
Experience with CRISPR-based screening approaches is a plus
Company
Proclinical Staffing
At Proclinical Staffing, our life science recruitment services support our partners with permanent and contract vacancies by connecting them with specialist talent across the globe.
51-200 employees
Funding
Current Stage
Growth StageCompany data provided by crunchbase