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Pfizer · 1 month ago

Principal Scientist, Biotherapeutic Characterization, Biosensor Assays

United States - Massachusetts - Cambridge

Full-time

Onsite

Senior Level, Lead/Staff

4+ years exp

Pfizer is a global leader in biopharmaceuticals dedicated to delivering breakthroughs that change patients' lives. The Principal Scientist will be responsible for characterizing biotherapeutics through the development of Biosensor assays and ensuring high-quality analytical data is delivered to project teams. This role requires strong collaboration skills and the ability to manage multiple projects within a fast-paced research environment.

BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine

No H1B

Responsibilities

Characterize biotherapeutics by developing Biosensor assays, triaging early-stage hits, assisting lead optimization, and candidate selection

Rigorous analysis of kinetic biomolecular binding interaction data and detailed reporting that impacts project portfolio advancement

Present Biosensor data at multidiscipline project team meetings and regularly contribute strategic recommendations that progress programs

Develop and implement innovative value-added Biosensor assays, explore novel technologies, and new instrumentation that expand capabilities

Collaborate with cross-functional teams to help accelerate the pace of discovery to support multiple research areas

Qualification

Biosensor assaysProtein-protein bindingBiotherapeutic drug discoverySurface plasmon resonance (SPR)BiacoreAutomation workflowsData managementCommunicationPresentation skillsCollaboration skills

Required

A PhD with 4 years or MS with 9+ years of relevant experience in Biochemistry, Biology, or related discipline

Experience with the biotherapeutic drug discovery process

Comprehensive applied experience developing and executing protein-protein binding Biosensor assays, including surface plasmon resonance (SPR), to characterize biotherapeutic candidates

Excellent communication, presentation, and data management skills

Ability to quickly adapt within a fast-paced, dynamic, and innovation driven scientific research environment