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TakedaPharmaceutical Nordics AB · 2 days ago

Global Therapeutic Research Lead - Immunology

Boston, MA

Full-time

Hybrid

Director/Executive

$208K/yr - $327K/yr

15+ years exp

Takeda Pharmaceutical Nordics AB is a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. The Global Therapeutic Research Lead (GTRL) will be responsible for driving research projects to the clinic and leading drug discovery efforts in the Gastroenterology and Inflammation areas, while providing mentorship to team members and managing external partnerships.

Pharmaceuticals

Responsibilities

Lead and manage one or more ‘Top 10’ drug discovery projects, overseeing the entire drug discovery process from target identification to preclinical development. (Top 10 projects are well validated targets that are focused on strategically aligned modalities with substantial clinical and commercial potential)

Responsible for the articulation and ownership of the project strategy, developed in partnership with internal stakeholders

Contribute to strategy for future portfolio investment, particularly within the Inflammation and Immunology area including advising on which projects should be Top 10 projects

Evaluate and prioritize potential drug candidates based on scientific, medical, and commercial considerations

Represent all core expertise for the project

Partner with Clinical and Translational teams to refine asset strategy

Ensure alignment to the therapeutic area strategy (i.e., Clinical Development)

Understand and align with the commercial team for asset commercial value within the TA

Provide guidance and mentorship to global project team members, stimulating enterprise thinking and fostering their professional growth and development

Mentor future and more junior project leads and elevate drug discovery capability across Research

Collaborate with cross-functional teams and partners (e.g., DMPK, Pharmaceutical Sciences) within and outside Takeda to drive project delivery

Pipeline and enterprise impact through effective partnering with multiple internal and external collaborators

Provide strategic, process, and operational leadership for successful Top 10 Project delivery

Foster a culture of innovation and scientific excellence within the matrixed drug discovery team, promoting collaboration, knowledge sharing, and continuous learning

Become a world leading scientific expert in the projects you lead

Oversee the design and execution of experiments, data analysis, and interpretation to enable decision-making and optimize drug discovery efforts

Stay abreast of the latest advancements in drug discovery, emerging technologies, and industry trends, applying this knowledge to enhance drug discovery strategies

Build and maintain relationships with key stakeholders, including academic institutions, research organizations, and industry partners inclusive of serving on joint external governance committees across the globe

Represent Takeda externally for the Gastroenterology and Inflammation Drug Discovery Unit and play a key role in evaluating external opportunities, serving as an effective ambassador for Takeda’s global business development brand

Qualification

Drug discovery leadershipImmunology expertiseClinical development experienceStrategic partnershipsProject managementMentorshipCollaborationCommunication skillsProblem-solving

Required

PhD degree in a scientific discipline with 15+ years experience, or MS with 21+ years experience, or BS with 23+ years experience

Expected to have at least 10-12 years industry and relevant subject matter expertise within Immunology and Inflammation and at least 10-12 years global management experience, including working effectively with matrix teams

Extensive experience in leading drug discovery teams and managing drug discovery/development projects, preferably in a pharmaceutical or biotechnology setting covering gastroenterology and inflammation

Deep understanding of the drug discovery process, including target identification, hit-to-lead optimization, and preclinical development, anticipating, and removing roadblocks

Proven track record of leading numerous projects, ideally 5+ projects, across discovery from target inception to Candidate Nomination or beyond

Played a major role in 3+ INDs

Has delivered clinical development assets, must include experience with biologics and preferably across multiple modalities

Excellent and inclusive leadership with the ability to inspire and motivate diverse teams towards achieving ambitious goals

Reputation as a proactive, solutions-oriented leader who engages relevant expertise no matter where it resides

Strong business acumen and understanding of the pharmaceutical industry, including regulatory requirements and commercial considerations with relevant knowledge and expertise for specific modalities

Exceptional communication and presentation skills, with the ability to effectively communicate complex scientific concepts to diverse audiences

Proven ability to build and maintain collaborative relationships with internal and external stakeholders across a matrixed organization

Strong problem-solving and decision-making abilities, with a focus on data-driven decision making

Demonstrated success in building and managing strategic partnerships with academic institutions, research organizations, and industry collaborators