Amgen · 1 day ago
Sr Dir Machine Learning
United States
Full-time
Remote
Director/Executive
10+ years expAmgen is a biotechnology company dedicated to serving patients living with serious illnesses. The Sr. Director of Machine Learning will lead algorithmic innovation, oversee data pipelines, and mentor talent while advancing reinforcement learning applications across various scientific and operational domains.
BiotechnologyHealth CareManufacturingPharmaceutical
Responsibilities
Define enterprise RL roadmaps, landmarks, and success metrics; drive early hands-on prototypes as the capability matures
Architect simulation environments, reward structures, and training loops for scientific and operational RL use cases
Lead algorithmic innovation and technical decisions across model-based RL, policy gradient methods, and actor-critic architectures
Advance RL for scientific domains such as protein design, docking, and structural modeling; expand RL beyond R&D into Manufacturing, Supply Chain, and Commercial applications
Oversee data pipelines, curation, and feature engineering supporting RL experimentation and multi-modal model training
Guide RL pilots from proof-of-concept through production deployment, ensuring ML Ops rigor—versioning, automated testing, monitoring, and continuous training
Partner deeply with biology, engineering, platform teams, product teams, and enterprise AI groups to integrate RL into existing workflows and systems
Mentor and develop talent; drive innovation, safety, and scientific/engineering excellence
Evaluate emerging research, open-source frameworks, and frontier methods (e.g., multi-agent RL, RLHF, simulation-based optimization) for enterprise adoption
Communicate outcomes, technical decisions, and implications to leadership and key stakeholders
Qualification
Required
Doctorate degree and 5 years of Artificial Intelligence/ Machine Learning experience
OR Master's degree and 8 years of Artificial Intelligence/ Machine Learning experience
OR Bachelor's degree and 10 years of Artificial Intelligence/ Machine Learning experience
PhD or equivalent experience in ML, RL, or related fields
10+ years AI/ML
5+ years reinforcement learning leadership
Preferred
Proficient Python, PyTorch/TensorFlow, distributed training
Contributions to AlphaFold-like or large-scale scientific AI
Publications at NeurIPS, ICML, or ICLR
Biotech, pharma, or healthcare domain exposure
Familiarity with GxP, HIPAA, or FDA guidance
Experience leading AI Centers of Excellence
Patents or open-source RL contributions
Prior collaborations with academia or top AI labs
Benefits
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible
Company
Amgen
Amgen is a biotechnology company that develops and manufactures human therapeutics for various illnesses and diseases.
10001+ employees
H1B Sponsorship
Amgen has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (429)
2024 (485)
2023 (485)
2022 (540)
2021 (460)
2020 (444)
Funding
Current Stage
Public CompanyTotal Funding
$28.5B2022-12-12Post Ipo Debt· $28.5B
1983-06-17IPO
Leadership Team
Robert Bradway
Chairman and Chief Executive Officer
Jay Bradner
Executive Vice President of R&D, and Chief Scientific Officer
Recent News
2026-01-13
Genetic Engineering News
2026-01-12
Company data provided by crunchbase