Immunome, Inc. · 1 day ago
Sr. Scientist, Analytical Development and QC, Biologics
Bothell, Washington, United States
Full-time
Onsite
Senior Level
$154K/yr - $174K/yr
5+ years expImmunome is a clinical-stage targeted oncology company focused on developing innovative cancer therapies. They are seeking a Senior Scientist in Analytical Development & QC to lead physicochemical analytical method development for their Antibody Drug Conjugate (ADC) portfolio and collaborate with external laboratories.
BiopharmaBiotechnologyMedicalPharmaceutical
Responsibilities
Develop and execute physicochemical analytical methods for ADC characterization, release, and stability testing using LC, CE, icIEF, and MS technologies
Implement CMC analytical method development activities within Immunome laboratories in alignment with phase-appropriate requirements
Collaborate with Contract Testing Laboratories (CTLs) to develop, qualify, and validate robust analytical testing methodologies
Serve as Analytical Lead for assigned pipeline programs, providing scientific guidance on data interpretation and analytical strategy
Contribute to preparation of analytical sections of regulatory submissions and technical reports
Draft and review method protocols, development reports, and method transfer packages to support GMP activities
Maintain awareness of emerging analytical technologies and evolving regulatory expectations, integrating relevant innovations into Immunome’s analytical and QC strategy
Collaborate cross-functionally with Discovery, Process Chemistry, Formulation Development, and Quality teams to ensure analytical approaches align with broader program needs
Qualification
Required
Bachelor's, Master's, or PhD in Analytical Chemistry, Biochemistry, or a related scientific discipline
A minimum of 5 years of industry experience supporting CMC analytical method development with direct ADC experience
Demonstrated experience in analytical method development, qualification/validation, and QC support for biologics or ADCs
Experience managing external CDMO/CTL analytical activities, including oversight of timelines, data quality, and deliverables
Hands-on experience supporting analytical method transfer to external laboratories and/or GMP environments
Strong working knowledge of analytical separation principles for biologics and complex conjugated modalities
Proven experience in phase-appropriate analytical method development for ADC product characterization, release, and stability testing
Strong understanding of ADC product attributes, including conjugation chemistry, linker-payload properties, and DAR-related quality considerations
Hands-on expertise with advanced analytical platforms, including capillary electrophoresis, HPLC/UPLC, and mass spectrometry
Ability to interpret complex analytical data and translate results into actionable development insights
Strong communication skills and ability to collaborate effectively across cross-functional teams
Demonstrated ability to manage multiple priorities, troubleshoot complex technical challenges, and operate effectively in a dynamic, fast-paced environment
Company
Immunome, Inc.
Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted therapies designed to improve outcomes for cancer patients.
51-200 employees
H1B Sponsorship
Immunome, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
Funding
Current Stage
Public CompanyTotal Funding
$998.85MKey Investors
JPEO-CBRNDU.S. Department of DefenseRobin Hood Ventures
2025-12-16Post Ipo Equity· $400M
2025-01-29Post Ipo Equity· $150M
2024-02-13Post Ipo Equity· $230M
Leadership Team
Clay Siegall
President and CEO
Purnanand D. Sarma
President & CEO
Recent News
2026-01-09
BioWorld Financial Watch
2025-12-19
thefly.com
2025-12-18
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