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AstraZeneca · 18 hours ago

Associate Director, Translational Research Hematology R&D

US - Waltham - MA

Full-time

Hybrid

Lead/Staff, Director/Executive

$265K/yr - $397K/yr

5+ years exp

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. The Associate Director will lead a team in the development of translational assays and deliver translational data to support the Hematology Translational Medicine Department’s strategy, particularly focusing on multiple myeloma and blood cancer precursor conditions.

BiopharmaBiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine

Comp. & Benefits

H1B Sponsor Likely

Responsibilities

The AD is responsible for the design and execution of non-clinical and translational experiments to understand hematological tumor biology, supporting the AZ portfolio. This work includes, but is not limited to, testing target expression after treatment, novel MRD technologies, reverse translation approaches to identify mechanisms of resistance, and informing new combinations across multiple heme indications

This role will lead translational assay development supporting programs in multiple myeloma and blood cancer precursor conditions, as well as other heme malignancies indications

Integrate Translational Medicine Research Scientists with broader drug development teams, including translational medicine (TM leads, data scientists, etc.), discovery, and clinical groups

Manage a team of lab-based scientists to support Hematology Translational Medicine research efforts

Apply literature reviews, protocols, networking and prior laboratory experience to advance clinical and pre-clinical aims of the Hematology Translational Medicine group

Demonstrate excellent organizational and communication skills for cross-functional interactions

Writes research papers, abstracts, technical reports, regulatory documents and SOPs

Performs all duties in compliance with internal SOPs and external regulations

Qualification

Translational researchHematology-oncology expertiseBiomarker developmentNGSFlow cytometryQPCRClinical trial collaborationLiterature reviewTeam managementCommunication skillsOrganizational skills

Required

Doctorate degree in immunology, molecular biology or related field with experience in hematology-oncology

Minimum of 5 years of industry experience including managerial experience of junior scientists and technicians

Strong background in oncology, cell biology, immunology, and small molecule drug discovery, ADCs, cell therapies or TCEs

Strong hands-on experience with translational lab methodologies applicable to biomarker studies in pre-clinical models and clinical trials (eg. NGS, flow cytometry, qPCR, etc) including data analysis of large datasets

Collaborating with clinical teams and working with clinical trial samples including for e.g. peripheral blood and bone marrow. Knowledge of clinical protocol design and biospecimen logistics

Robust track record of scientific achievement, and innovation approaches as evidenced by publication record

Excellent interpersonal skills, ability to work as an integral member of a team, and proficiency in training and managing a team

Strong written and oral communication skills

Proven excellence in designing, executing, and interpreting cancer biomarker studies in preclinical models and clinical trials, including biomarker development, validation, and clinical application

Benefits

Qualified retirement programs

Paid time off (i.e., vacation, holiday, and leaves)

Health, dental, and vision coverage in accordance with the terms of the applicable plans

Company

AstraZeneca

Glassdoor4.1

AstraZeneca is a pharmaceutical company that discovers, develops, manufactures, and markets prescription medicines. It is a sub-organization of Investor.

Founded in 1999

Cambridge, Cambridgeshire, GBR

10001+ employees

https://www.astrazeneca.com

H1B Sponsorship

AstraZeneca has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

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Trends of Total Sponsorships

2021 (2)

2020 (11)