Lead Technical Project Manager jobs in United States
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McKesson · 5 hours ago

Lead Technical Project Manager

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. The Lead Technical Project Manager plays a critical role in driving the successful delivery for AI/ML & Advanced Analytics initiatives across the organization, managing the project lifecycle and ensuring alignment with strategic objectives.

BiopharmaBiotechnologyHealth CareInformation TechnologyPharmaceutical
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H1B Sponsor Likelynote

Responsibilities

Define and own the end-to-end roadmap for AI/ML initiatives, translating business objectives into actionable programs such as demand forecasting models, NLP-driven chatbots, or predictive analytics. Manage the intake of new requests, gather necessary information for accurate sizing, confirm business value, and ensure alignment with strategic priorities. Evaluate and prioritize initiatives by balancing business value, technical feasibility, resource availability, and associated risks. Use portfolio management tools (Jira, Confluence, MS Project, Smartsheet) to maintain visibility and alignment from ideation through deployment
Serve as the central coordinator, orchestrating collaboration across data scientists, ML engineers, data engineers, business analysts, and IT teams. Ensure high-quality pipelines and seamless integration into production systems through APIs, cloud ML services, and CI/CD pipelines
Oversee day-to-day delivery of AI/ML projects using Agile practices (Scrum, SAFe, Kanban). Manage sprints, backlogs, epics, and stories within Jira/Confluence, tracking dependencies and deliverables. Identify risks (e.g., limited data availability, model performance gaps, infrastructure bottlenecks) and implement mitigation strategies. Enforce robust testing standards including unit testing, model validation, A/B testing, and performance benchmarking
Act as a trusted partner to business stakeholders and product teams, translating business use cases into clear technical AI/ML requirements. Establish measurable KPIs (accuracy, ROI, adoption rates, productivity impact). Provide regular executive-level updates, communicating technical progress clearly and concisely
Ensure compliance with regulatory frameworks (HIPAA, GDPR, SOC 2, FDA). Promote Responsible AI principles (fairness, transparency, explainability). Drive documentation, audit readiness, model cataloging, data lineage traceability, and reproducibility. Establish governance for MLOps including model versioning, drift monitoring, and automated retraining
Define and track KPIs across technical, business, and delivery dimensions (accuracy, precision/recall, F1 score, ROI, adoption). Provide transparent portfolio health reporting to leadership
Champion innovation by promoting emerging technologies (Generative AI, LLMOps, AutoML). Collaborate with architecture teams to modernize ML stack (Databricks Lakehouse, Vertex AI, Azure ML). Drive accelerators such as reusable code libraries, pre-trained models, and standardized MLOps pipelines

Qualification

AI/MLAgile PracticesProject ManagementCross-Functional CollaborationGovernance FrameworksGenerative AIDatabricksStakeholder ManagementEffective Communication

Required

Strong technical acumen in AI/ML and analytics
Excellent project management skills
Ability to communicate effectively with technical and non-technical audiences
Proven ability to align cross-functional teams and remove delivery bottlenecks
Degree or equivalent and typically requires 10+ years of relevant experience. Less years required if has relevant Master's or Doctorate qualifications

Preferred

Experience with Generative AI, LLMOps, AutoML
Familiarity with platforms like Databricks, Vertex AI, Azure ML
Knowledge of governance frameworks and Responsible AI principles

Benefits

Annual bonus
Long-term incentive opportunities

Company

McKesson

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McKesson distributes medical supplies, information technology, and care management products and services.

H1B Sponsorship

McKesson has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (149)
2024 (129)
2023 (82)
2022 (142)
2021 (144)
2020 (154)

Funding

Current Stage
Public Company
Total Funding
unknown
1994-11-18IPO

Leadership Team

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Brian Tyler
CEO
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Jim McAuliffe
CFO
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Company data provided by crunchbase