Bristol Myers Squibb · 4 weeks ago
Senior Scientist, Analytical Development, Cell Therapy
Seattle 400 Dexter - WA - US
Full-time
Onsite
Mid, Senior Level
$129K/yr - $156K/yr
3+ years expBristol Myers Squibb is a company that transforms the lives of patients through innovative work in various departments. They are seeking a highly motivated Senior Scientist to join their Cell Therapy Analytical Development department, where the role involves developing and troubleshooting LC-MS assays to advance gene-edited cell therapy development.
BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
Responsibilities
Act as a subject matter expert to design, develop, optimize, and standardize robust physiochemical methods—including LC, LC-MS, CE, SEC/AEX-MALS, preparative LC-MS—for sample quality control and the characterization of oligonucleotides and proteins
Maintain and troubleshoot instrumentation (e.g., UPLC, LC-MS, CE, MALS, LC-MS) to ensure high performance, reliability, and minimal downtime in support of critical workflows
Maintain meticulous laboratory notebooks and manage routine sample analysis requests
Present scientific results and observations to colleagues at cross functional meetings, management, and at meetings with external partners
Author, review and approve technical documents, including methods, protocols, reports, and regulatory submissions
Good knowledge of cGMP and ICH/FDA/EMEA guidance
Complete regulatory, site, and department training requirements on a timely basis
Qualification
Required
A PhD with 3+ (BS with 10+) years of experience in pharmaceutical research, development, or related industry experience
Expert in HPLC and LC-MS instrumentation from multiple vendors (e.g. Vanquish, Waters, OrbiTrap, Q-Exactive), including setup, operating, troubleshooting and maintaining (i.e. vent and clean) as well as method development
Proficient in software such as Empower, Xcalibur, Chromeleon, Biopharma finder, Protein metrics etc
Strong background and experience in separations sciences, including but not limited to SEC, RP, IEX, HILIC and CE
Expert in developing LC-MS and LC-MS/MS methods for large biomolecules (e.g., mAb, ADC, proteins) including Intact mass, reduced mass, peptide mapping, and glycan mapping
Lead the development of new LC-MS and LC-MS/MS analytical methods for the characterization of nucleic acid-based compounds: oligonucleotides, RNA and DNA-based modalities
Ability to work effectively in a collaborative team setting and in a rapidly changing environment with frequent changes in priorities, which require strong organizational skills
Strong written and oral communication skills
Preferred
Experience in cGMP environment is preferred
Benefits
Health Coverage: Medical, pharmacy, dental, and vision care.
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
Paid Time Off
US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
Company
Bristol Myers Squibb
At Bristol Myers Squibb, we work every day to transform patients’ lives through science.
10001+ employees
H1B Sponsorship
Bristol Myers Squibb has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
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Trends of Total Sponsorships
2025 (247)
2024 (278)
2023 (231)
2022 (180)
2021 (181)
2020 (169)
Funding
Current Stage
Public CompanyTotal Funding
$29.32BKey Investors
Venrock
2025-11-05Post Ipo Debt· $5.74B
2024-02-14Post Ipo Debt· $13B
2023-10-30Post Ipo Debt· $4.5B
Leadership Team
Charles Bancroft
CFO
Cristian Massacesi
Executive Vice President, Chief Medical Officer and Head of Development
Recent News
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