Senior Copilot Engineer jobs in United States
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Bristol Myers Squibb · 2 hours ago

Senior Copilot Engineer

Bristol Myers Squibb is a company dedicated to transforming the lives of patients through innovative work in various departments. They are seeking a Senior Copilot Engineer to design, develop, and deploy advanced AI and automation solutions, leveraging technologies like Microsoft Copilot Studio and AWS cloud services.

BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
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H1B Sponsor Likelynote

Responsibilities

Design, develop, and deploy custom AI/Copilot solutions using Microsoft Copilot Studio, Azure OpenAI, Azure AI Foundry, and AWS AI/ML services
Build RAG pipelines with vector databases, embeddings, and contextual grounding strategies
Develop and integrate AI Search capabilities using Azure AI Search, AWS Kendra, or Elasticsearch to power intelligent retrieval and semantic grounding
Implement grounding, semantic reasoning, and conversational orchestration using Azure Cognitive Search, custom APIs, and multi-cloud pipelines
Build Power Apps, including model-driven and canvas applications
Develop automation workflows using Power Automate (Flows) integrated with AI and enterprise data sources
Design and implement SPFx solutions (web parts, extensions) integrated with Copilot Studio and Power Platform components
Integrate copilots and AI-driven features with SharePoint, Teams, Power Apps, and other Microsoft 365 services
Create custom connectors for Power Platform to extend AI and Copilot capabilities across enterprise services
Provide technical leadership on AI/LLM architecture, prompt engineering, semantic search, and multi-cloud solution engineering
Support 3rd-level LLM model development, optimization, and registration for enterprise platforms
Participate in AI/ML audits and compliance reviews across global environments
Apply engineering best practices for Copilot, AI, Power Platform, and cloud solution development, testing, deployment, and governance
Collaborate with business stakeholders to identify AI/Copilot and automation opportunities, validate use cases, and translate requirements into technical solutions
Deliver POCs, pilots, and scalable enterprise implementations across Azure and AWS
Ensure all solutions meet enterprise security, privacy, compliance, and Responsible AI standards
Manage engineering tasks across multiple initiatives while maintaining high-quality deliverables

Qualification

AI engineeringMicrosoft Power PlatformMicrosoft 365 extensibilityCloud technologiesMicrosoft Copilot StudioAzure AI FoundryAWS cloud technologiesAI search technologiesSPFx developmentPythonC#TypeScriptStakeholder engagementCommunication skills

Required

Bachelor's or Master's degree in Computer Science, Engineering, or a related field
5-8 years of experience in AI/ML engineering, cloud development, or enterprise solution delivery
6-8 years of hands-on Microsoft Power Platform development experience
Practical experience with major AI/ML platforms including Microsoft Azure, AWS, and Google Cloud
Strong background developing solutions in regulated or large-scale enterprise environments
Deep expertise across the Microsoft 365 ecosystem: Azure, SharePoint, Teams, Purview, Defender, and Power Platform
Hands-on experience with Microsoft Copilot Studio (prompt flows, orchestration, connectors)
Experience with Azure AI Foundry / Azure OpenAI, including prompt engineering, grounding, and model deployments
Extensive experience with Power Apps, Power Automate, and custom Power Platform connectors
Proficiency in SPFx (SharePoint Framework) development and Microsoft Graph integrations
Strong working knowledge of AI search technologies such as Azure Cognitive Search, AWS Kendra, and Elasticsearch
Experience building cloud-native AI workflows with Azure Functions, AWS Lambda, and modern orchestration patterns
Strong understanding of RAG architectures, vector databases, semantic search, and contextual grounding
Proficiency in Python, C#, or TypeScript for custom development and integration
Familiarity with Responsible AI practices, MLOps, and end-to-end AI lifecycle management
Experience developing enterprise copilots, plugins, and extensibility solutions for Microsoft 365 and Power Platform
Excellent communication and stakeholder engagement skills

Benefits

Health Coverage: Medical, pharmacy, dental, and vision care.
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
Paid Time Off
US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

Company

Bristol Myers Squibb

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At Bristol Myers Squibb, we work every day to transform patients’ lives through science.

H1B Sponsorship

Bristol Myers Squibb has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (247)
2024 (278)
2023 (231)
2022 (180)
2021 (181)
2020 (169)

Funding

Current Stage
Public Company
Total Funding
$29.32B
Key Investors
Venrock
2025-11-05Post Ipo Debt· $5.74B
2024-02-14Post Ipo Debt· $13B
2023-10-30Post Ipo Debt· $4.5B

Leadership Team

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Charles Bancroft
CFO
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Cristian Massacesi
Executive Vice President, Chief Medical Officer and Head of Development
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Company data provided by crunchbase