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Day One Biopharmaceuticals · 17 hours ago

Vice President, Product Team Leader

United States

Full-time

Remote

Director/Executive

$300K/yr - $330K/yr

15+ years exp

Day One Biopharmaceuticals is focused on advancing first- or best-in-class medicines for childhood and adult diseases. They are seeking a strategic VP, Product Team Leader to lead cross-functional clinical-stage development programs from Phase 1 through commercialization, ensuring alignment with corporate objectives and effective execution of the program plan.

BiopharmaBiotechnologyHealth CarePharmaceutical

No H1B

Responsibilities

Lead strategy creation and alignment of internal and external experts with overall product vision for one or more Day One product teams, resulting in a comprehensive Integrated Development Plan, ensuring all program initiatives are in pursuit of a coherent product vision

Hold primary accountability for the forward progress of Day One’s development programs, as measured by the achievement of milestones and other key performance indicators defined by the Product Team (PT) and endorsed by senior leadership, effectively balancing scientific, regulatory and commercial objectives

Work closely with functional leaders and relevant sub-teams, leading the PT in development, evolution, and execution of an integrated global strategic project plan, including scientific, clinical, regulatory, CMC, commercial, and corporate/business considerations, doing so through building trusted relationships and ensuring alignment in pursuit of program and corporate goals

Communicate program strategy, progress, milestones, timelines, budget and drive decisions in senior leadership forums such as the Operating Committee. Distill program strategy and progress for presentation to key stakeholders such as the Board of Directors

In partnership with Clinical Research, Medical Affairs, Commercial leadership and other relevant stakeholders, establish and maintain key external stakeholder relationships relevant to the programs and products success

In partnership with Program Management, set direction, milestones and goals for the team, ensuring program strategy is aligned with corporate objectives and functional strategies

Lead the PT in developing and meeting the requirements of the relevant target product profiles

Work with Program Management to create and maintain an integrated program timeline detailing the development paths to registration across treatment settings and geographies

Work with Program Management to monitor team goals and team effectiveness

Work with the PT and Program Management to ensure timely execution of the project plan within allocated

Anticipate major risks to achievement of key deliverables and put appropriate mitigation plans in place

Perform integrated scenario planning/assessment for the development plan

Work with medical affairs and the commercial organization on scientific messaging and competitive positioning

Support the commercial organization in forecasting, launch, and portfolio planning efforts

Lead the PT in development of cross-functional program budget and resource drivers and Long-Range Plan (LRP) assumptions and work with functional heads to ensure appropriate program resources are in place

Partner with the Head of R&D, other Product Team Leads, the R&D Leadership Team and other key stakeholders such as Finance, Commercial, and Technical Operations and People to iteratively optimize the Product Team-centered model across the Day One portfolio

Partner with the Head of R&D, Finance, the Head of the Program Management Organization, and other key stakeholders in support of portfolio prioritization tools and processes as needed to support Day One’s portfolio growth

Qualification

Drug developmentOncology drug developmentCross-functional leadershipRegulatory requirementsStrategic planningTeam motivationAnalytical skillsCommunicationCollaboration skills

Required

Bachelor's degree is required

Advanced degree (e.g. MS, MD, PhD, PharmD, MBA or equivalent) in life sciences or commensurate experience strongly preferred

15+ years of industry experience in drug development, including a comprehensive understanding of early- and late-stage clinical drug development, precision medicine and global regulatory requirements; the preferred candidate will have had direct functional or project-oriented experience across the spectrum of development, from late preclinical through marketing authorization, inclusive of life cycle management

5+ years of cross-functional project leadership in oncology drug development or rare disease

Understanding of the manufacturing considerations of small molecules, biologics and ADC therapeutics

Demonstrated ability to integrate and synthesize data, assess strategic alternatives, and forge alignment of functions and executive management across business objectives, development strategy, and operational plans

Experienced partnering across the spectrum of functional areas to advance program objectives and a demonstrated understanding of and appreciation for commercial requirements

Track record in leading teams to strong results in a matrix environment and demonstrated skills in motivation of teams

Ability to cultivate excellent cross-functional collaborations

Strategic thinker with strong decision-making and analytical skills

Excellent communication and influencing skills with a proven ability to work with executive management to obtain endorsement of development plans and budget/personnel support; the ideal candidate will translate a multidimensional asset strategy across all stakeholders, including the Board of Directors, incorporating both the competitive landscape and corporate objectives

Ability to perform in a fast-paced, dynamic, cross-functional, and mission-driven environment; prior work experience in small biotech highly Mission-driven leadership that fosters inspiring, high-performing teams acting with accountability and empowerment to achieve clear program goals is essential

Willingness to assume full product accountability for both the strategic and operational plan, including program budget management in pursuit of clear program objectives, is critical

Foster and facilitate a culture where diverse perspectives are heard in pursuit of optimal decision making, with skills to negotiate through challenging conversations to achieve positive outcomes; Humility and high self-awareness carry a high premium in Day One's culture