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Immunome, Inc. · 4 hours ago

Principal Scientist, Pathology

Bothell, WA

Full-time

Onsite

Senior Level, Lead/Staff

$170K/yr - $237K/yr

1+ years exp

Immunome, Inc. is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. The Principal Scientist, Pathology will provide anatomic pathology expertise and collaborate with various teams to integrate tissue-based insights into the company's oncology portfolio.

BiopharmaBiotechnologyMedicalPharmaceutical

H1B Sponsor Likely

Responsibilities

Serve as a scientific contributor providing anatomic pathology expertise, disease pathogenesis insight, and tissue-based biomarker interpretation for discovery and translational programs

Contribute as a subject matter expert to discussions on target biology, model selection, in vitro/in vivo alignment, target liability, and translational relevance across multiple therapeutic programs

Perform histopathologic evaluation of tissues from discovery, preclinical, and clinical studies to assess target expression, pathology phenotypes, mechanism of action, and biomarker distribution

Apply and support the use of tissue-based platforms (ex. IHC, ISH, multiplex imaging, and digital image analysis) to enable qualitative and quantitative assessments

Integrate pathology findings with in vitro data and multi-omics outputs (e.g., transcriptomics, proteomics) to support mechanistic understanding and translational hypotheses

Prepare high-quality pathology summaries and written reports to support internal data review, program decisions, and study documentation

Participate as a pathology representative on cross-functional project teams and contribute to internal and external scientific discussions

Communicate pathology findings clearly and effectively to diverse audiences, including discovery scientists, translational researchers, and clinicians

Contribute to scientific publications, abstracts, presentations, and internal knowledge-sharing efforts related to tissue-based translational research

Qualification

Veterinary anatomic pathologyTumor biologyImmuno-oncologyIHC/ISHDigital pathology toolsMultiplex imagingTissue-based biomarkersAnalytical skillsCollaborationCommunication skills

Required

DVM/VMD, or equivalent

Board certification in veterinary pathology (ACVP/ECVP) required

Ph.D., PharmD, MD, or equivalent in a relevant scientific discipline (e.g. cancer biology, toxicology, molecular pathology)

Experience in IHC/ISH, multiplex imaging, digital pathology tools, and interpretation of tissue-based biomarkers

1-4 years' experience in discovery, translational research, or nonclinical sciences preferred

Solid foundation in tumor biology, cancer immunology, and molecular oncology

Experience designing, executing, interpreting, and reporting exploratory pathology studies

Familiarity with comparative biomarker assay development

Ability to assess translational relevance and target liability using integrated in vitro and in vivo data

Strong analytical and problem-solving skills with the ability to manage multiple projects in a dynamic research environment

Excellent written and verbal communication skills, with the ability to convey complex pathology concepts clearly and concisely

Collaborative mindset with the ability to work effectively across multidisciplinary internal and external teams

Preferred

1-4 years' experience in discovery, translational research, or nonclinical sciences preferred

Company

Immunome, Inc.

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted therapies designed to improve outcomes for cancer patients.

Founded in 2008

Exton, Pennsylvania, USA

51-200 employees

https://immunome.com

H1B Sponsorship

Immunome, Inc. has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

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Trends of Total Sponsorships

2025 (1)