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R&D Partners · 10 hours ago

Senior System Engineer

Pleasanton, CA

Contract

Onsite

Senior Level

$59.35/hr - $74.19/hr

5+ years exp

R&D Partners is a global functional service provider specializing in scientific, clinical research, and engineering. They are seeking a highly motivated Senior System Engineer to drive feasibility, development, and integration of complex multi-disciplinary systems in the field of molecular detection technologies and bioinformatics. The role involves collaborating with various teams to ensure system-level performance and operational scalability.

Staffing Agency

Responsibilities

Systems Development, Integration & Analysis

Drive system-level development activities across wet lab workflows, instruments, and data pipelines for next generation diagnostic solutions

Perform hands-on system integration and troubleshooting of workflows including sample extraction, library preparation, molecular detections, and data transfer

Partner with assay, software and bioinformatics teams to ensure seamless integration of sequencing output with downstream analysis pipelines

Contribute to system architecture, requirements definition

Apply statistical analysis and Design of Experiments (DoE) methodologies (e.g., JMP, ANOVA, regression) to characterize, optimize, and set subsystem specifications

Verification, Validation & On Market support

Plan, design and execute verification and validation (V&V) test cases to ensure comprehensive coverage of requirements

Analyze test results for accuracy, validity, and relevance to user needs

Support post-launch troubleshooting and field investigations through failure mode and root cause analyses

Collaboration & Influence

Represent Systems Engineering in cross-functional project teams on key topics such as requirements management, defect management, system integration, etc

Collaborate closely with assay scientists, software developers, hardware engineers, and bioinformaticians to align on end-to-end workflows

Contribute to system documentation, including requirements, specifications, integration plans, and verification results

Identify and lead opportunities for workflow simplification, automation, and continuous improvement

Qualification

Systems EngineeringSequencing WorkflowsBioinformatics PipelinesStatistical AnalysisTroubleshooting ExperienceDoE MethodologiesAnalytical SkillsPythonCommunication SkillsCollaboration

Required

Bachelor's or Master's degree with 10 years of relevant industry experience or PhD degree with 5 years of experience

Major in Systems Engineering, Bioengineering, Biomedical Engineering

Hands-on industrial experience with sequencing related workflows, including nucleic acid extraction, library preparation, and sequencing

Proven lab troubleshooting experience in sequencing workflows and PCR-based workflows

Experience with statistical tools and DoE methodologies (JMP, regression, ANOVA) is required

Strong analytical and problem-solving skills with the ability to work independently

Excellent written and verbal communication skills to influence cross-functional stakeholders

Preferred

Exposure to bioinformatics/data processing pipelines for sequencing output (variant calling, data QC) is highly desirable

Familiarity with system-level product development in life sciences instrumentation is a plus

Experience across multiple product life-cycle stages is a plus

Experience in digital PCR platforms is desirable

Experience with developing In-vitro Diagnostic products is desirable

Experience in implementing workflow on semiconductor based sensing devices or microfluidic devices is desirable

Scripting/programming experience (Python, R, or equivalent) is a plus

You are a fast learner who thrives at the interface of biology, technology, and data

You want to translate complex scientific workflows into reliable, scalable system solutions

You are collaborative, curious, and driven to make an impact across diverse disciplines, and is comfortable operating as an individual contributor with broad cross-functional influence