Vertex Pharmaceuticals · 5 hours ago
Computational Genomics Research Scientist
San Diego, CA
Full-time
Hybrid
New Grad, Entry, Mid Level
$112K/yr - $168K/yr
0+ years expVertex Pharmaceuticals is a global biotechnology company that invests in scientific innovation. They are seeking a computational biologist to join their Data and Computational Sciences organization, where the role involves leveraging computational biology to accelerate the development of transformative therapies for serious human diseases.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Proactively collaborate with cross‑functional project teams as the computational biology expert to identify key scientific questions that can be addressed through human genetics, genomics, sequencing, and computational analyses
Design and execute studies across diverse omics, including bulk RNA‑seq, whole‑genome sequencing, single‑cell RNA‑seq, spatial transcriptomics, and human genetics
Perform sophisticated computational analyses of internal and external datasets, integrating deep critical thinking, statistical rigor, domain expertise, and best practices from the literature to generate actionable insights
Incorporate publicly available genomic resources (e.g., GTEx, gnomAD, FinnGen, UK Biobank) to contextualize and interpret internal data
Distill complex analyses and scientific results into clear presentations, including key take-home messages and recommendations for next steps to a broad audience
Author study reports, white papers, and manuscripts to support internal decision-making and external communications including regulatory filings
Partner with the DCS method development team to develop innovative methods and improve usability, accuracy, and robustness of existing ones
Qualification
Required
PhD degree (or Master's degree) in computational biology, bioinformatics, human genetics, genomics, systems biology, bioengineering, or a related field with 0–3 years (or 3+ years for Master's degree) of productive, relevant industry or post-doc experience
A proven track record of stand-out excellence in the analysis, visualization, and interpretation of genomic data (such as next-generation sequencing (NGS)) or human genetic data
Demonstrated ability to work across cross-functional teams, ensuring timely progress
Superior communication skills, demonstrating confidence and versatility in presenting verbally to diverse audiences and writing technical documents
Deep scientific understanding of genetic variation in human disease, molecular biology, and cellular biology
Expertise with rapidly applying computational methods and bioinformatics tools to large-scale data
Proficiency with R and/or python, and high-performance computing systems; solid understanding of statistics
A team-oriented growth mindset that welcomes feedback from others and supports other team members; a positive attitude that enthusiastically tackles and overcomes challenges
Preferred
A proven track record in the analysis, visualization, and interpretation of genomic and next-generation sequencing (NGS) data
Solid scientific understanding of gene editing, the role of genetic variation in human disease, molecular biology, and cellular biology
Expertise with applying computational methods and bioinformatics tools to large-scale data
Solid understanding of statistics
Benefits
Medical, dental and vision benefits
Generous paid time off (including a week-long company shutdown in the Summer and the Winter)
Educational assistance programs including student loan repayment
A generous commuting subsidy
Matching charitable donations
401(k)
Company
Vertex Pharmaceuticals
Vertex Pharmaceuticals is focused on the discovery and development of small molecule drugs for the treatment of serious diseases.
5001-10000 employees
H1B Sponsorship
Vertex Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (188)
2024 (150)
2023 (111)
2022 (164)
2021 (112)
2020 (80)
Funding
Current Stage
Public CompanyTotal Funding
$657.31MKey Investors
Janssen Belgium
2024-07-10Post Ipo Secondary· $1.11M
2022-05-17Post Ipo Equity· $50M
2009-12-03Post Ipo Equity· $443M
Leadership Team
Reshma Kewalramani
CEO and President
Nina Devlin
Senior Vice President, Chief Communications Officer
Recent News
2026-01-12
Company data provided by crunchbase