Nesco Resource ยท 17 hours ago
Sr. Systems Engineer - NGS
Pleasanton, CA
Full-time
Onsite
Senior Level
$60/hr - $83.53/hr
5+ years expNesco Resource is seeking a highly motivated Senior System Engineer to join their End-to-End Solution Integration Chapter supporting Next-Generation Diagnostic Solutions. The role involves driving the feasibility, development, and integration of complex multi-disciplinary systems and collaborating with various teams to ensure technical robustness and operational scalability.
ConsultingHuman ResourcesStaffing Agency
Responsibilities
Drive system-level development activities across wet lab workflows, instruments, and data pipelines for next generation diagnostic solutions
Perform hands-on system integration and troubleshooting of workflows including sample extraction, library preparation, molecular detections, and data transfer
Partner with assay, software and bioinformatics teams to ensure seamless integration of sequencing output with downstream analysis pipelines
Contribute to system architecture, requirements definition
Apply statistical analysis and Design of Experiments (DoE) methodologies (e.g., JMP, ANOVA, regression) to characterize, optimize, and set subsystem specifications
Plan, design and execute verification and validation (V&V) test cases to ensure comprehensive coverage of requirements
Analyze test results for accuracy, validity, and relevance to user needs
Support post-launch troubleshooting and field investigations through failure mode and root cause analyses
Represent Systems Engineering in cross-functional project teams on key topics such as requirements management, defect management, system integration, etc
Collaborate closely with assay scientists, software developers, hardware engineers, and bioinformaticians to align on end-to-end workflows
Contribute to system documentation, including requirements, specifications, integration plans, and verification results
Identify and lead opportunities for workflow simplification, automation, and continuous improvement
Qualification
Required
PhD degree with related field with 5+ years of relevant industry experience is highly valued
Master's degree with 10+ years of relevant industry experience
Bachelor's degree with 10+ years of relevant industry experience
hands-on industrial experience with sequencing related workflows, including nucleic acid extraction, library preparation, and sequencing
Proven lab troubleshooting experience in sequencing workflows and PCR-based workflows
Experience with statistical tools and DoE methodologies (JMP, regression, ANOVA) is required
Strong analytical and problem-solving skills with the ability to work independently
Excellent written and verbal communication skills to influence cross-functional stakeholders
Preferred
Exposure to bioinformatics/data processing pipelines for sequencing output (variant calling, data QC) is highly desirable
Familiarity with system-level product development in life sciences instrumentation is a plus
Experience across multiple product life-cycle stages is a plus
Experience in digital PCR platforms is desirable
Experience with developing In-vitro Diagnostic products is desirable
Experience in implementing workflow on semiconductor based sensing devices or microfluidic devices is desirable
Scripting/programming experience (Python, R, or equivalent) is a plus
Benefits
MEC (Minimum Essential Coverage) plan that encompasses Medical, Vision, Dental, 401K, and EAP (Employee Assistance Program) services.
Company
Nesco Resource
Nesco Resource s an Staffing and Recruiting firm.
501-1000 employees
Funding
Current Stage
Late StageLeadership Team
Michael McDonald
Executive Vice President of Finance and Chief Accounting Officer
Recent News
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2023-12-24
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2023-12-24
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