Alnylam Pharmaceuticals · 19 hours ago
Senior Director, Cyber Defense
Cambridge, MA
Full-time
Hybrid
Director/Executive
$230K/yr - $310K/yr
15+ years expAlnylam Pharmaceuticals is pioneering RNA interference (RNAi) therapeutics and is seeking a Senior Director of Cyber Defense to lead their global Cyber Defense program. This role involves overseeing security operations, threat detection, and incident response while driving a multi-year security maturity roadmap in alignment with business growth.
BiotechnologyHealth CareMedicalPharmaceuticalTherapeutics
Responsibilities
Lead Alnylam’s global Cyber Defense program, including Security Operations Center (SOC), Threat Intelligence, Incident Response, and Insider Risk
Drive a multi-year security modernization roadmap aligned with business growth and regulatory requirements
Oversee day-to-day operational excellence in threat detection, response, and vulnerability management
Develop and execute strategies for proactive threat hunting, purple teaming, and continuous improvement of detection capabilities
Establish and maintain cyber crisis management and incident response frameworks, including executive tabletop exercises
Partner with senior business and technology leaders to embed security into enterprise initiatives and protect critical assets
Manage and mentor talent fostering a culture of accountability and resilience
Collaborate with Identity, GRC, and IT teams to advance Zero Trust architecture and unified security controls
Define and track key performance metrics (MTTD, MTTR, maturity scores) to measure and report program effectiveness
Engage with external partners and vendors to enhance capabilities and validate security posture
Qualification
Required
Bachelor's degree in Computer Science, Information Security, Engineering, or related field
15+ years of progressive experience in cybersecurity operations, threat detection, incident response, or digital risk management
10+ years of leadership experience, including managing global or distributed cyber defense or SOC teams
Deep familiarity with cybersecurity frameworks such as NIST CSF, NIST 800-53, HIPAA, PCI DSS (aligned with internal training expectations for senior leaders)
Demonstrated success overseeing a modern cyber defense function that includes Security Operations Center (SOC), Threat Intelligence, Incident Response & Forensics, Insider Threat programs
Preferred
Master's degree or MBA preferred
Industry-recognized certifications strongly preferred (e.g., CISSP, CISM, GIAC)
Benefits
Comprehensive benefits including medical, dental, and vision coverage
Life and disability insurance
Lifestyle reimbursement program
Flexible spending and health savings accounts
401(k) with a generous company match
Paid time off
Wellness days
Holidays
Two company-wide recharge breaks
Generous family resources and leave
Company
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
1001-5000 employees
H1B Sponsorship
Alnylam Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (18)
2021 (19)
2020 (7)
Funding
Current Stage
Public CompanyTotal Funding
$4.55BKey Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO
Leadership Team
Yvonne Greenstreet
Chief Executive Officer
Jeff Poulton
Chief Financial Officer
Recent News
2026-01-13
2026-01-13
Company data provided by crunchbase