Genentech · 10 hours ago
Sr Plant/Reliability Engineer, Dixon - Site Services
Genentech is seeking a seasoned engineer to join their Facilities & Engineering Asset Management team as a Plant & Reliability Engineer. This role focuses on ensuring the safe, efficient, and reliable operation of campus-wide facilities, utilities, and equipment, while leading initiatives to enhance system uptime and implement reliability-centered maintenance practices.
BiotechnologyLife ScienceManufacturing
Responsibilities
Support facilities, utilities, and equipment (FUE) at the SSF site (South San Francisco and Dixon) and provide technical system ownership of critical mechanical, electrical and process infrastructure
Work collaboratively with stakeholders to ensure that the site facilities, utilities, and equipment are maintained and operated using Reliability Centered Maintenance (RCM) principles and practices
Lead and contribute to strategic planning for Reliability Engineering
Apply RCM to GMP and Non-GMP equipment within the South San Francisco (SSF), and Dixon (DXN) campuses with the aim of increasing uptime and optimizing the Reliability, Maintainability and Availability (RMA) of systems
Use existing databases (e.g., SAP CMMS, qualified and non-qualified Facilities Data Historian (FDH) and Building Automation System (BAS)), updating as required, to perform Pareto analysis and follow up to improve results
Provide SME input to the site equipment criticality and risk ranking process
Participate in and drive improvement through the Daily Huddles
Produce and use metrics to monitor and drive improvements in the Equipment Reliability program
Manage recommendations and metrics associated with the monitoring of equipment and maintenance program performance
Ensure that the appropriate level of support, investigation and follow-up is pursued for actionable trends, emerging patterns, and identified problems or issues
Make equipment design change recommendations including evaluating and reporting the cost benefit of changes to improve reliability
Create and maintain critical spare parts programs
Support quality and productivity improvements
Prepare the organization to support continuous improvements in reliability
Assuring that reliability and maintainability principles are integrated into all large and small capital projects
Maintain communication with engineering and project management on Facility related projects
Drive proper collection and summarization of system and parts data for handover from projects to operations
Responsible for creation of Maintenance Strategies, Work Instructions, Maintenance Plans, Spare Parts and BOM’s
Directly supporting capital projects by providing design input, specifying system requirements and overseeing installation of FUE equipment
Direct communication and collaboration with project team (Architects, Engineers, and General Contractors), Genentech stakeholders/SMEs to ensure project accounts for asset maintenance and reliability management/considerations and total cost of ownership throughout design, execution and closeout
Ensure the timely leadership, problem investigation and analysis through the conduct and facilitation of Root Cause Analysis (RCA) for applicable equipment failures or trends
Ensuring equipment performance and meeting KPIs
Providing technical knowledge of system design, functionality and requirements
Maintaining our assets: keeping engineering documentation and risk/criticality assessments up to date, defining maintenance strategies and plans, including critical spare parts
Providing condition assessment and system oversight throughout the asset lifecycle
Auditing processes and documents for compliance
Collaborating closely with other Plant Engineers, Facilities Operations and Maintenance (FOM) and our Integrated Facility Management (IFM) service provider, to provide technical and engineering support for Site Operations
Proactively identifying and recommending opportunities for improvement including: reducing costs and operational risks, improving operational efficiencies, increasing quality and safety, clarifying and simplifying processes
Evaluating and improving the reliability of all campus systems and ensuring business continuity through asset lifecycle management
Ensure campus FUE systems are operated and maintained according to best practices
Actively partnering with Site Services; Safety, Health and Environment (SHE); Design & Construction and PTAA project teams (designers, architects, general contractors, etc.) to provide guidance on the safe and efficient operations of campus systems
Lead and implement the Asset Management Strategy and associated program
Develop and maintain a strategic capital improvement plan for the site
Assess repair versus replacement options, providing input to site on new equipment design, specification, and purchase decisions
Ensure that the maintenance strategies and actions employed are appropriate to the criticality of facilities, utilities and equipment
Ensure that standard designs, design specifications, installation guidance documents, operating and maintenance procedures incorporate the appropriate maintenance and reliability principals and considerations
Qualification
Required
Bachelor of Science in Mechanical, Chemical, Industrial or equivalent field of Engineering
8 or more years of relevant experience in design and operation of facilities, equipment, and utilities within high tech, industrial, life sciences, or chemical manufacturing industries
Experience with optimization of equipment operation
2 or more years of experience working in large campus environment
Understanding of interface with automation and controls including: Building Automation Systems (BAS), Programmable Logic Controllers (PLCs), Data Historians, etc
Working knowledge of ANSI/ASHRAE, NEMA, NFPA, EPA, and OSHA standards as well as relevant chemical industry specific standards and documentation (piping and instrumentation diagrams, process flow diagrams)
Requires overall working knowledge of Reliability Centered Maintenance (RCM) with experience in the application and analysis of various Predictive Maintenance (PdM) methods, including at least 2 years' experience with rotating equipment, and electrical systems including MCCs and building electrical distribution systems
Proficient, experienced or working knowledge in facilitating failure analysis with one or more of these methods: Failure Modes and Effects Analysis (FMEA), Failure Modes, Effects and Criticality Analysis (FMECA – U.S. Dept of Defense Military Standard 1629A), Reliability Centered Maintenance (RCM), Failure Reporting, Analysis and Corrective Action System (FRACAS), The “Five Why's” or other Root Cause Failure Analyses (RCFA) methods
Formal training in some level of statistics and/or statistical process control required
Experienced in gathering, categorizing and analyzing large amounts of data
Proficiency with SAP CMMS (Computerized Maintenance Management System)
Preferred
Certification as a Maintenance / Reliability Professional (CMRP or equivalent) strongly preferred
Experience and understanding of current good manufacturing practices (cGMPs and cGXP) strongly desired
Lean or Six Sigma Certification strongly desired
Experience investigating and correcting system corrosion issues
Experience in plant engineering and R&D, manufacturing, commercial operations
Experience in design, construction and operation of LEED certified buildings
Advanced degree in Mechanical, Chemical or Industrial Engineering or equivalent
Professional Engineering License in Mechanical or Chemical Engineering
Experience with Biosecurity/Biosafety Containment Strategies, Working knowledge of standard BSL-2/BSL-3/BSL-4
Certification in Project Management (PMP or equivalent)
Benefits
A discretionary annual bonus may be available based on individual and Company performance.
Company
Genentech
Genentech is a biotechnology research company that specializes in genetic testing and personalized medicines.
H1B Sponsorship
Genentech has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (167)
2024 (148)
2023 (150)
2022 (178)
2021 (121)
2020 (158)
Funding
Current Stage
Public CompanyTotal Funding
unknown2009-03-26Acquired
1999-07-20IPO
1976-01-01Series Unknown
Leadership Team
Recent News
2026-01-07
MarketScreener
2026-01-06
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