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Merck · 13 hours ago

Principal Scientist, Protein Engineering

San Diego, CA

Full-time

Hybrid

Senior Level, Lead/Staff

$157K/yr - $247K/yr

7+ years exp

Merck is a global health care leader with a diversified portfolio of prescription medicines, vaccines, and animal health products. The role involves leading biologics discovery and development, focusing on antibodies and bispecific molecules, while collaborating with various teams across the organization.

BiotechnologyHealth CareMedicalPharmaceutical

Comp. & Benefits

H1B Sponsored

Responsibilities

Lead the design, engineering and characterization of innovative biologics, including antibodies and bispecific molecules

Direct the Protein Sciences team in the production and purification of antibodies in mammalian cell lines including transient HEK, CHO; and antigen and protein reagents required for the drug discovery portfolio

Drive innovation by contributing to exploratory programs and technology development

Strategic project leadership in Immunology Biologics, partnering cross-functionally with teams in discovery, pharmacokinetics, pharmacodynamics, toxicology, CMC, translational sciences and translational medicine

Lead and mentor a team of scientists

Foster a high-performance culture of collaboration, engagement, self-accountability and inclusion

Effectively partner across multidisciplinary interfaces to achieve organizational objectives

Stay abreast of external advancements in the relevant scientific fields

Promote the external reputation of the Discovery Biologics Department by contributing to publications and conference presentations

Qualification

Protein EngineeringTherapeutic Protein DesignImmunologyProject LeadershipProtein CharacterizationProtein PurificationTeam ManagementCommunicationLeadershipCollaboration

Required

Bachelor's (with 14 years), Master's (with 10 years) or Ph.D. (with 7 years) in Immunology, Molecular Biology, Biochemistry, Cellular Biology or related field and relevant experience

Deep scientific knowledge across workflows and domains integral to the discovery and development of protein therapeutics

Expertise in therapeutic protein design, engineering and characterization

Experience advancing a biotherapeutic programs from Discovery into Development and driving the application of scientific or platform innovations

Demonstrated passion for, and a track record of talent development

Champion for a diverse and inclusive culture

Excellent verbal and written communication skills

Strong external reputation through publications, presentations, and scientific community engagement

Antibodies

Biologics

Communication

Immunology

Leadership