Frederick National Laboratory for Cancer Research · 2 weeks ago
Laboratory Automation Design Engineer
The Frederick National Laboratory for Cancer Research is a Federally Funded Research and Development Center that focuses on addressing urgent problems in biomedical sciences. The Laboratory Automation Design Engineer will lead the design, integration, and validation of automated laboratory systems to enable standardized organoid testing and cell culture workflows.
BiotechnologyHealth CareMedicalOncology
Responsibilities
Lead the design, digital modeling, and implementation of automated systems supporting SOM Center operations
Define the project scope of work and develop system requirements documents and functional specifications
Conduct design reviews and ensure compliance with laboratory safety and operational standards
Perform equipment testing, system validation, and performance qualification
Oversee the development of SOM Center’s core automation systems, including: Organoid Functional Testing System: supports high-throughput characterization, drug testing and microplate-based assays using microplate readers and high-content imaging systems
Organoid Cell Culture Support System: automates workflows for organoid culturing and sample preparation
Utilize SolidWorks and related CAD tools for digital design of custom frameworks and modular automation enclosures
Determine and implement safety and containment requirements, including enclosure design for operator protection and sample sterility
Manage the fabrication and assembly of custom parts, fixtures, and laboratory apparatuses
Maintain detailed design documentation, engineering drawings, and configuration control
Provide engineering support for new SOM Center laboratory buildouts, including space planning, equipment layout, and utility coordination
Evaluate and advise on building infrastructure modifications (e.g., floor load capacity, lab ventilation, safety systems)
Coordinate with Facilities Maintenance and Engineering (FME) to implement building services such as alarm systems, nitrogen gas, and liquid nitrogen supply
Support the phased transition of the Molecular Pharmacology Laboratory (MPL) to a new facility, including: Disassembly, relocation, and reassembly of two large automated HTS systems
Design and implementation of mechanical upgrades during the move
Post-move validation and qualification of systems
Provide engineering-based counsel to scientific staff on automation design and system utilization
Mentor and develop junior engineers, fostering a culture of technical excellence and safety
Perform hands-on testing, including teaching robot positions, paths, and verifying instrument drivers
Troubleshoot hardware and software issues associated with automation platforms and peripheral devices
Coordinate or perform routine preventive maintenance and ensure uptime of automated systems
Ensure traceable documentation of all engineering activities, test results, and system updates
Qualification
Required
Possession of Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency
In addition to the education requirement, a minimum of five (5) years of progressively responsible experience
Demonstrated proficiency with SolidWorks or equivalent CAD tools for mechanical design
Experience with liquid handling systems and robotic platforms
Prior industry or biotech experience
Proven ability to develop engineering documentation, system specifications, and technical reports
Strong understanding of laboratory safety, containment, and ergonomic design principles
Excellent organizational, communication, and leadership skills
Ability to work 100% onsite at the Fort Detrick campus in Frederick, MD
Ability to travel occasionally (<5%) for conferences, vendor collaboration, or offsite meetings
Ability work effectively in a collaborative, fast-paced, research-intensive environment at a National Laboratory
Ability to obtain and maintain a security clearance
Preferred
Background in facility planning, lab construction coordination, or infrastructure engineering in a research environment
Prior experience managing or mentoring junior engineers or technicians
Familiarity with federal laboratory safety and biosafety standards (e.g., BSL-2 environments)
Exposure to regulatory or quality management systems in research settings
Benefits
Health and Wellness programs
Income Protection
Paid Leave
Retirement
Company
Frederick National Laboratory for Cancer Research
Frederick National Laboratory for Cancer Research specializes in developing biomedical research and technology to improve human health.
Funding
Current Stage
Late StageRecent News
2025-10-14
2025-09-29
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