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PacBio · 11 hours ago

Senior Director, Information Technology

Menlo Park, CA

Full-time

Hybrid

Director/Executive

$196K/yr - $294K/yr

12+ years exp

PacBio is a premier life science technology company that designs, develops, and manufactures advanced sequencing solutions to help scientists and clinical researchers resolve genetically complex problems. The Senior Director, IT is responsible for leading the global IT organization, partnering closely with executive leadership to enable business strategy and operational excellence through secure and scalable technology solutions.

BiotechnologyChemicalGeneticsLife ScienceMedical

No H1B

Responsibilities

Lead, develop, and scale a high-performing IT organization, including managers and senior technical leaders

Foster a culture of accountability, service excellence, security awareness, and continuous improvement

Define and execute a multi-year IT strategy and technology roadmap aligned with PacBio’s business objectives

Partner closely with Finance, Manufacturing, R&D, Quality, Legal, and Commercial teams to support business needs and continually improve operational efficiency

Own PacBio’s cybersecurity strategy, posture, and operations, including prevention, detection, response, and recovery

Ensure compliance with ISO 27001, SOX, and other applicable regulatory and audit requirements, including leading, coordinating, and interfacing directly with internal and external SOX auditors

Lead IT risk management, security governance, incident response planning, and third-party risk management

Establish and maintain security policies, standards, and controls across infrastructure, applications, and data

Partner with internal and external auditors to support audits and remediation activities

Ensure IT systems supporting regulated processes comply with validation and quality requirements (e.g., GxP)

Own IT governance frameworks, including SDLC, change management, access controls, and data governance

Maintain audit readiness and documentation across systems and processes. Oversee enterprise architecture, application portfolio management, and system lifecycle planning

Lead the operation and evolution of hybrid infrastructure, including on-premises and cloud environments

Support high-performance computing (HPC) and large-scale storage platforms for R&D and data-intensive workloads

Drive reliability, scalability, and performance of mission-critical systems

Drive modernization initiatives, including cloud adoption, automation, and legacy system rationalization

Own the IT budget, forecasting, and cost optimization initiatives

Manage strategic vendor relationships, system integrators, and managed service providers

Qualification

IT leadershipCybersecurity strategySOX complianceISO 27001 certificationHybrid IT managementEnterprise architectureApplication managementData governanceJira Service DeskSAPSalesforceCommunication skills

Required

Bachelor's degree in Information Systems, Computer Science, Engineering, or a related field; advanced degree preferred

12+ years of progressive IT experience, including significant leadership at the director or senior director level

Experience in a public company, preferably within life sciences, biotechnology, or a regulated industry

Demonstrated experience with SOX compliance, remediation, and internal/external audits

Hands-on leadership experience with ISO 27001 security frameworks and certification efforts

Strong knowledge of system validation, enterprise architecture, application management, and IT governance

Proven experience managing hybrid IT environments, including cloud, on-premises infrastructure, HPC, and storage

Experience with and understanding of Jira Service Desk, SAP, Anaplan, Salesforce, PLM, and MES (Siemens Opcenter)

Provide strategic oversight and guidance for PacBio's SAP ERP platform, ensuring alignment with business objectives, compliance requirements, and enterprise architecture standards

Excellent executive communication skills and ability to influence across functions